Why should we care about neonatal hyperbilirubinemia in 2011?

被引:5
作者
Raimondi, Francesco [1 ]
Maffucci, Rosalba [1 ]
Milite, Paola [1 ]
Ferrara, Teresa [1 ]
Borrelli, Angela Carla [1 ]
Sodano, Angela [1 ]
Capasso, Letizia [1 ]
机构
[1] Univ Naples Federico 2, Div Neonatol, Dept Pediat, Naples, Italy
关键词
bilirubin; jaundice; phototherapy; neonate; BILIRUBIN; RISK; PERMEABILITY; MANAGEMENT; DISEASE;
D O I
10.3109/14767058.2011.607660
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Recent research links serum bilirubin levels to a positive function in human health. Yet in the neonate hyperbilirubinemia is associated to damage to the CNS and beyond. This article summarizes the evidence for the double edged role of bilirubin with a focus on the neonatal period. Also we briefly describe some of the current shortcomings in the treatment of neonatal hyperbilirubinemia.
引用
收藏
页码:83 / 84
页数:2
相关论文
共 10 条
[1]   Confirmed association between neonatal phototherapy or neonatal icterus and risk of childhood asthma [J].
Aspberg, Sara ;
Dahlquist, Gisela ;
Kahan, Thomas ;
Kallen, Bengt .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2010, 21 (04) :E733-E739
[2]   Perinatal risk factors for childhood type 1 diabetes in Europe - The EURODIAB substudy 2 study group [J].
Dahlquist, GG ;
Patterson, C ;
Soltesz, G .
DIABETES CARE, 1999, 22 (10) :1698-1702
[3]   Current Italian practices regarding the management of hyperbilirubinaemia in preterm infants [J].
Dani, Carlo ;
Poggi, Chiara ;
Barp, Jacopo ;
Romagnoli, Costantino ;
Buonocore, Giuseppe .
ACTA PAEDIATRICA, 2011, 100 (05) :666-669
[4]   Serum Bilirubin and Risk of Respiratory Disease and Death [J].
Horsfall, Laura J. ;
Rait, Greta ;
Walters, Kate ;
Swallow, Dallas M. ;
Pereira, Stephen P. ;
Nazareth, Irwin ;
Petersen, Irene .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (07) :691-697
[5]   Effect of hyperbilirubinemia on intestinal permeability in healthy term newborns [J].
Indrio, Flavia ;
Raimondi, Francesco ;
Laforgia, Nicola ;
Riezzo, Gieuseppe ;
Polimeno, Lorenzo ;
Francavilla, Ruggiero .
ACTA PAEDIATRICA, 2007, 96 (01) :73-75
[6]   The Clinical Syndrome of Bilirubin-Induced Neurologic Dysfunction [J].
Johnson, Lois ;
Bhutani, Vinod K. .
SEMINARS IN PERINATOLOGY, 2011, 35 (03) :101-113
[7]  
Maisels MJ, 2004, PEDIATRICS, V114, P297
[8]   Neonatal hyperbilirubinemia increases intestinal protein permeability and the prevalence of cow's milk protein intolerance [J].
Raimondi, Francesco ;
Indrio, Flavia ;
Crivaro, Valeria ;
Araimo, Gabriella ;
Capasso, Letizia ;
Paludetto, Roberto .
ACTA PAEDIATRICA, 2008, 97 (06) :751-753
[9]   Unconjugated bilirubin modulates the intestinal epithelial barrier function in a human-derived in vitro model [J].
Raimondi, Francesco ;
Crivaro, Valeria ;
Capasso, Letizia ;
Maiuri, Luigi ;
Santoro, Pasquale ;
Tucci, Maria ;
Barone, Maria Vittoria ;
Pappacoda, Serena ;
Paludetto, Roberto .
PEDIATRIC RESEARCH, 2006, 60 (01) :30-33
[10]   Gilbert syndrome and ischemic heart disease:: a protective effect of elevated bilirubin levels [J].
Vítek, L ;
Jirsa, M ;
Brodanová, M ;
Kaláb, M ;
Marecek, Z ;
Danzig, V ;
Novotny, L ;
Kotal, P .
ATHEROSCLEROSIS, 2002, 160 (02) :449-456