Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system

被引：17

作者：

Smulko, Janusz ^{[1
]}

Chludzinski, Tomasz ^{[1
]}

Majchrzak, Tomasz ^{[2
]}

Kwiatkowski, Andrzej ^{[1
]}

Borys, Sebastian ^{[3
]}

Jaimes-Mogollon, Aylen Lisset ^{[4
]}

Manuel Duran-Acevedo, Cristhian ^{[4
]}

Geovanny Perez-Ortiz, Omar ^{[5
]}

Ionescu, Radu ^{[6
]}

机构：

[1] Gdansk Univ Technol, Fac Elect Telecommun & Informat, Narutowicza 11-12, PL-80233 Gdansk, Poland

[2] Gdansk Univ Technol, Fac Chem, Dept Analyt Chem, Narutowicza 11-12, PL-80233 Gdansk, Poland

[3] Univ Ctr Maritime & Trop Med, Powstania Styczniowego 9B, PL-81519 Gdynia, Poland

[4] Univ Pamplona, Elect Engn Program, Multisensor Syst & Pattern Recognit Res Grp GISM, Pamplona, Colombia

[5] Univ Pamplona, Clin UNIPAMPLONA, Cucuta, Colombia

[6] Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Kreutzwaldi 62, EE-51006 Tartu, Estonia

来源：

MEASUREMENT | 2022年 / 190卷

基金：

欧盟地平线“2020”;

关键词：

Electronic nose; Low cost gas sensors; Dengue disease; Exhaled breath analysis; Classification algorithms; RANDOM FOREST; DIAGNOSIS; ARRAY; DRIFT; LUNG;

D O I：

10.1016/j.measurement.2022.110733

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue - a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOC (TM) breath sampler. Two strategies were assessed for breath samples measurement: either direct transfer from the BioVOC (TM) into the sensors test chamber, or storage in Tenax TA sorbent tubes followed by VOCs release through thermal desorption and then transfer into sensors test chamber. DC sensor resistances were recorded and processed by multivariate classifier algorithms to detect infected patients. The experimental studies were run on a group of 26 individuals (16 dengue diagnosed patients and 10 control volunteers). The detection accuracy of dengue patients was over 90%.

引用

页数：9

共 36 条

[1] Electronic Nose with Digital Gas Sensors Connected via Bluetooth to a Smartphone for Air Quality Measurements [J].