Cryptococcal lymphadenitis and immune reconstitution inflammatory syndrome: Current considerations

被引：3

作者：

Kuttiatt, Vijesh

Sreenivasa, Prarthana

Garg, Isha ^{[2
]}

Shet, Anita ^{[1
,3
,4
]}

机构：

[1] St Johns Natl Acad Hlth Sci, Dept Paediat, St Johns Res Inst, Bangalore, Karnataka, India

[2] St Johns Natl Acad Hlth Sci, Dept Pathol, Bangalore, Karnataka, India

[3] St Johns Natl Acad Hlth Sci, Dept Pediat, Bangalore, Karnataka, India

[4] Karolinska Inst, Div Global Hlth, Stockholm, Sweden

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 2011年 / 43卷 / 08期

关键词：

Cryptococcal lymphadenitis; immune reconstitution inflammatory syndrome ( IRIS); human immunodeficiency virus (HIV); ACTIVE ANTIRETROVIRAL THERAPY; HIV-RELATED LYMPHADENOPATHY; NEEDLE-ASPIRATION-CYTOLOGY; POSITIVE PATIENT; RISK-FACTORS; NORTH-INDIA; MENINGITIS; AIDS; MANIFESTATION; INFECTION;

D O I：

10.3109/00365548.2011.574293

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

HIV-related immune reconstitution inflammatory syndrome (IRIS) is increasingly being recognized in regions with a high burden of opportunistic infections. We describe an unusual manifestation of IRIS-'unmasking' cryptococcal lymphadenitis in a patient shortly after initiation of antiretroviral therapy. Epidemiology, clinical features and management of cryptococcal IRIS with reference to lymphadenitis presentation are briefly reviewed. Early and accurate diagnosis is essential for appropriate management. Standard antifungal therapy along with continuation of antiretroviral therapy is recommended. Cases with severe inflammation may benefit from anti-inflammatory drugs/corticosteroids. Unusual manifestations like lymphadenitis pose diagnostic difficulties in regions with a high prevalence of tubercular lymphadenitis.

引用

页码：664 / 668

页数：5

共 29 条

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