Nine novel C-21 steroidal glycosides substituted with orthoacetate from Dregea sinensis var. corrugata

被引：12

作者：

Liu, Yunbao ^{[1
,2
,3
]}

Qu, Jing ^{[1
,2
,3
]}

Yu, Shishan ^{[1
,2
,3
]}

Tang, Wenzhao ^{[1
,2
,3
]}

Liu, Jing ^{[1
,2
,3
]}

Hu, Youcai ^{[1
,2
,3
]}

Ma, Shuanggang ^{[1
,2
,3
]}

机构：

[1] Peking Union Med Coll, Minist Educ, Key Lab of Bioact Substances & Resources Utilizat, Beijing 100050, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[3] Peking Union Med Coll, Inst Mat Med, Beijing 100050, Peoples R China

来源：

STEROIDS | 2008年 / 73卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Dregea sinensis var. corrugata; asclepiadaceae; steroidal glycosides; orthoacetate;

D O I：

10.1016/j.steroids.2007.09.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine novel steroidal glycosides substituted with the orthoacetate groups, compounds 1-5 based on the aglycon of 12-O-acetyl-20-O-benzoyl-dihydrosarcostin 8,14,18-orthoacetate and compounds 6-9 based on the aglycon of 12-O-acetyl-20-O-benzoyl-dihydrosarcostin 14,17,18-orthoacetate, were isolated from Dregea sinensis var. corrugata. Their structures were deduced on the basis of chemical and spectral evidences. Compound 1 showed moderate anti-inflammatory activity. (C) 2007 Published by Elsevier Inc.

引用

页码：184 / 192

页数：9

共 8 条

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Liu, Yunbao
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Liu, Jing
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[J]. STEROIDS, 2007, 72 (6-7) : 514 - 523
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