Evaluation of improved γ-aminobutyric acid production in yogurt using Lactobacillus plantarum NDC75017

被引:80
作者
Shan, Y. [1 ,2 ]
Man, C. X. [1 ,3 ]
Han, X. [4 ]
Li, L. [2 ]
Guo, Y. [2 ]
Deng, Y. [2 ]
Li, T. [2 ]
Zhang, L. W. [4 ]
Jiang, Y. J. [1 ,2 ,3 ]
机构
[1] Northeast Agr Univ, Natl Res Ctr Dairy Engn & Technol, Harbin 150086, Peoples R China
[2] Northeast Agr Univ, Dept Food Sci, Key Lab Dairy Sci, Minist Educ, Harbin 150030, Peoples R China
[3] Synerget Innovat Ctr Food Safety & Nutr, Harbin 150030, Peoples R China
[4] Harbin Inst Technol, Coll Food Sci & Engn, Harbin 150090, Peoples R China
基金
中国国家自然科学基金;
关键词
gamma-aminobutyric acid (GABA); Lactobacillus plantarum NDC75017; glutamate decarboxylase (GAD); yogurt; TRADITIONAL FERMENTED FOODS; ACE-INHIBITORY ACTIVITY; GLUTAMATE-DECARBOXYLASE; GABA PRODUCTION; BREVIS; MILK; BACTERIA; OPTIMIZATION; CULTURE; MANUFACTURE;
D O I
10.3168/jds.2014-8698
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Most gamma-aminobutyric acid (GABA)-producing microorganisms are lactic acid bacteria (LAB), but the yield of GABA is limited in most of these GABA-producing strains. In this study, the production of GABA was carried out by using Lactobacillus plantarum NDC75017, a strain screened from traditional fermented dairy products in China. Concentrations of substrate (L-monosodium glutamate, L-MSG) and coenzyme (pyridoxal-5-phosphate, PLP) of glutamate decarboxylase (GAD) and culture temperature were investigated to evaluate their effects on GABA yield of Lb. plantarum NDC75017. The results indicated that GABA production was related to GAD activity and biomass of Lb. plantarum NDC75017. Response surface methodology was used to optimize conditions of GABA production. The optimal factors for GABA production were L-MSG at 80 mM, PLP at 18 mu M, and a culture temperature of 36 degrees C. Under these conditions, production of GABA was maximized at 314.56 mg/100 g. Addition of Lb. plantarum NDC75017 to a commercial starter culture led to higher GABA production in fermented yogurt. Flavor and texture of the prepared yogurt and the control yogurt did not differ significantly. Thus, Lb. plantarum NDC75017 has good potential for manufacture of GABA-enriched fermented milk products.
引用
收藏
页码:2138 / 2149
页数:12
相关论文
共 50 条
[31]   pH Auto-Sustain-Based Fermentation Supports Efficient Gamma-Aminobutyric Acid Production by Lactobacillus brevis CD0817 [J].
Jia, Mengya ;
Zhu, Yisong ;
Wang, Lingqin ;
Sun, Tianyi ;
Pan, Hao ;
Li, Haixing .
FERMENTATION-BASEL, 2022, 8 (05)
[32]   Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and -aminobutyric acid production [J].
Lyu, Changjiang ;
Zhao, Weirui ;
Peng, Chunlong ;
Hu, Sheng ;
Fang, Hui ;
Hua, Yujiao ;
Yao, Shanjing ;
Huang, Jun ;
Mei, Lehe .
MICROBIAL CELL FACTORIES, 2018, 17
[33]   Food-grade γ-aminobutyric acid production by immobilized glutamate decarboxylase from Lactobacillus plantarum in rice vinegar and monosodium glutamate system [J].
Li-Li Yao ;
Jia-Ren Cao ;
Chang-Jiang Lyu ;
Fang-Fang Fan ;
Hong-Peng Wang ;
Hong-Wei Cao ;
Jun Huang ;
Le-He Mei .
Biotechnology Letters, 2021, 43 :2027-2034
[34]   Soy yogurt using Lactobacillus plantarum 200655 and fructooligosaccharides: neuroprotective effects against oxidative stress [J].
Choi, Ga-Hyun ;
Bock, Hyun-Ji ;
Lee, Na-Kyoung ;
Paik, Hyun-Dong .
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2022, 59 (12) :4870-4879
[35]   Lactic acid production from cassava fibrous residue using Lactobacillus plantarum MTCC 1407 [J].
Ray, Ramesh Chandra ;
Sharma, Piyush ;
Panda, Smita Hasini .
JOURNAL OF ENVIRONMENTAL BIOLOGY, 2009, 30 (05) :847-852
[36]   Improvement of γ-aminobutyric acid (GABA) production using cell entrapment of Lactobacillus brevis GABA 057 [J].
Choi, SI ;
Lee, JW ;
Park, SM ;
Lee, MY ;
Ji, GE ;
Park, MS ;
Heo, TR .
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 16 (04) :562-568
[37]   Production of gamma-aminobutyric acid by Lactobacillus brevis NCL912 using fed-batch fermentation [J].
Li, Haixing ;
Qiu, Ting ;
Huang, Guidong ;
Cao, Yusheng .
MICROBIAL CELL FACTORIES, 2010, 9
[38]   Biosynthesis of γ-aminobutyric acid (GABA) using immobilized whole cells of Lactobacillus brevis [J].
Jun Huang ;
Le-he Mei ;
Hong Wu ;
Dong-qiang Lin .
World Journal of Microbiology and Biotechnology, 2007, 23 :865-871
[39]   Biosynthesis of γ-aminobutyric acid (GABA) using immobilized whole cells of Lactobacillus brevis [J].
Huang, Jun ;
Mei, Le-He ;
Wu, Hong ;
Lin, Dong-qiang .
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2007, 23 (06) :865-871
[40]   Production of linoleic acid metabolites by different probiotic strains of Lactobacillus plantarum [J].
Aziz, Tariq ;
Sarwar, Abid ;
Al-Dalali, Sam ;
Din, Zia Ud ;
Megrous, Sarah ;
Din, Jalal Ud ;
Zou, Xin ;
Zhennai, Yang .
PROGRESS IN NUTRITION, 2019, 21 (03) :693-701