Immune Complexes: Not Just an Innocent Bystander in Chronic Viral Infection

被引：19

作者：

Wang, Taia T. ^{[1
]}

Ravetch, Jeffrey V. ^{[1
]}

机构：

[1] Rockefeller Univ, Lab Mol Genet & Immunol, New York, NY 10065 USA

来源：

IMMUNITY | 2015年 / 42卷 / 02期

关键词：

SYSTEMIC-LUPUS-ERYTHEMATOSUS;

D O I：

10.1016/j.immuni.2015.01.022

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Understanding of how persistent viral infection impacts humoral immunity is incomplete. In this issue of Immunity, Wieland et al. (2015) and Yamada et al. (2015) find that high amounts of IgG-antigen complexes formed during chronic lymphocytic choriomeningitis infection can interfere with Fcg-receptor-mediated effector activities, potentially contributing to immune dysfunction.

引用

页码：213 / 215

页数：4

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