Using a double blind controlled clinical trial to evaluate the function of a Diabetes Advisory System: a feasible approach?

被引：17
作者：
Hejlesen, OK
Andreassen, S
Frandsen, NE
Sorensen, TB
Sando, SH
Hovorka, R
Cavan, DA
机构：
[1] Univ Aalborg, Virtual Ctr Hlth Informat, Dept Med Informat, DK-9220 Aalborg, Denmark
[2] Sonderborg Hosp, Dept Med, Sonderborg, Denmark
[3] Odense Univ Hosp, Dept Endocrinol M, DK-5000 Odense, Denmark
[4] City Univ London, Dept Syst Sci, London EC1V 0HB, England
[5] Royal Bournemouth Hosp, Bournemouth Diabetes & Endocrine Ctr, Bournemouth, Dorset, England
来源：
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | 1998年 / 56卷 / 02期
关键词：
insulin dependent diabetes mellitus; double blind controlled clinical trial; decision support system; insulin-dosage adjustment;
D O I：
10.1016/S0169-2607(98)00023-6
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
This paper assesses the feasibility of using a double blind controlled clinical trial to evaluate the function of a decision support system by applying such a design to the evaluation of a Diabetes Advisory System (DIAS). DIAS is based on a model of the human carbohydrate metabolism and is designed as an interactive clinical tool, which can be used to predict the effects of changes in insulin dose or food intake on the blood glucose concentration in patients with insulin dependent diabetes. It can also be used to identify risk periods for hypoglycaemia, and to provide advice on insulin dose. The latter feature was evaluated in the present study. We believe double blind controlled clinical trials are prerequisites for clinical application of many decision support systems, and conclude that the present double blind controlled clinical trial is a suitable evaluation method for the function of DIAS. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：165 / 173
页数：9
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