Creating morphable logic gates using logical stochastic resonance in an engineered gene network

被引：50

作者：

Dari, Anna ^{[1
]}

Kia, Behnam ^{[1
,2
]}

Bulsara, Adi R. ^{[3
]}

Ditto, William ^{[1
]}

机构：

[1] Arizona State Univ, Sch Biol & Hlth Syst Engn, Tempe, AZ 85287 USA

[2] Arizona State Univ, Sch Elect Comp & Energy Engn, Tempe, AZ 85287 USA

[3] SPAWAR Syst Ctr Pacific, San Diego, CA 92152 USA

来源：

EPL | 2011年 / 93卷 / 01期

关键词：

LAMBDA-REPRESSOR; NOISE; CRO; EXPRESSION; CIRCUIT; SWITCH; CELL;

D O I：

10.1209/0295-5075/93/18001

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The idea of Logical Stochastic Resonance is adapted and applied to an autoregulatory gene network in the bacteriophage lambda. This biological logic gate can emulate or morph the AND and OR gates, through varying internal system parameters, in a noisy background. Such logic gates afford intriguing possibilities in the realization of engineered genetic networks, in which the function of the gate can be changed after the network has been assembled: this allows a single gene network to be used for many different applications in the emerging field of synthetic biology. Copyright (C) EPLA, 2011

引用

页数：5

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