Evaluation of the contraceptive efficacy, compliance, and satisfaction with the transdermal contraceptive patch system Evra: a comparison between adolescent and adult users

被引:8
作者
Bodner, Klaus [1 ,2 ]
Bodner-Adler, Barbara [3 ]
Gruenberger, Werner [2 ]
机构
[1] United Arab Emirates Univ, Fac Med & Hlth Sci, Dept Gynecol & Obstet, Al Ain, U Arab Emirates
[2] Hosp Rudolfstiftung, Dept Gynecol & Obstet, Vienna, Austria
[3] Al Ain Hosp, Dept Gynecol & Obstet, Al Ain, U Arab Emirates
关键词
Evra; Compliance; Satisfaction; Adolescents; Adult users; ORAL-CONTRACEPTIVES;
D O I
10.1007/s00404-010-1368-6
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Aim of the study was to evaluate Evra use in adolescents and compare the outcome with adult users. A total of 80 adolescents and 178 adults were followed-up at 1-, 3-, and 6-month interval with their compliance, satisfaction, cycle control, and adverse events being assessed. Compliance rate was generally higher among adult users (p < 0.05). Partial and complete patch detachment were both significantly higher among adolescents (p < 0.05). Self-reported side effects did not differ between both groups and declined over the time. Overall satisfaction was high among most subjects. Compared with previous contraception, most subjects reported better satisfaction with Evra (p < 0.05). This investigation observed an overall positive impression of Evra with good compliance among adolescent and adult users. This might be an effect of the convenience of the weekly dosing schedule. Compliance is of utmost importance in teenagers as this age group is at highest risk of unintended pregnancy.
引用
收藏
页码:525 / 530
页数:6
相关论文
共 27 条
[1]  
ABMA JC, 1997, VITAL HLTH STAT, V286, P1
[2]   Pharmacokinetics of a contraceptive patch (Evra™/Ortho Evra™) containing norelgestromin and ethinyloestradiol at four application sites [J].
Abrams, LS ;
Skee, DM ;
Natarajan, J ;
Wong, FA ;
Anderson, GD .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 53 (02) :141-146
[3]   Pharmacokinetics of norelgestromin and ethinyl estradiol delivered by a contraceptive patch (Ortho Evra™/Evra™) under conditions of heat, humidity, and exercise [J].
Abrams, LS ;
Skee, DM ;
Natarajan, J ;
Wong, FA ;
Leese, PT ;
Creasy, GW ;
Shangold, MM .
JOURNAL OF CLINICAL PHARMACOLOGY, 2001, 41 (12) :1301-1309
[4]   Evaluation of contraceptive efficacy and cycle control of a transdermal contraceptive patch vs an oral contraceptive - A randomized controlled trial [J].
Audet, MC ;
Moreau, M ;
Koltun, WD ;
Waldbaum, AS ;
Shangold, G ;
Fisher, AC ;
Creasy, GW .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (18) :2347-2354
[5]   Contraception: from accessibility to efficiency [J].
Bajos, N ;
Leridon, H ;
Goulard, H ;
Oustry, P ;
Job-Spira, N .
HUMAN REPRODUCTION, 2003, 18 (05) :994-999
[6]   Venous thromboembolism, myocardial infarction, and stroke among transdermal contraceptive system users [J].
Cole, J. Alexander ;
Norman, Heather ;
Doherty, Michael ;
Walker, Alexander M. .
OBSTETRICS AND GYNECOLOGY, 2007, 109 (02) :339-346
[7]   Satisfaction and compliance in hormonal contraception: The result of a multicentre clinical study on women's experience with the ethinylestradiol/norelgestromin contraceptive patch in Italy [J].
Crosignani P.G. ;
Nappi C. ;
Ronsini S. ;
Bruni V. ;
Marelli S. ;
Sonnino D. ;
Affronti G. ;
Benagiano G. ;
Benedetto C. ;
Bolis G. ;
Cianci A. ;
Fedele L. ;
Garsia A. ;
Genazzani A.R. ;
Gherzi R. ;
Masellis G. ;
Melis G. ;
Moscarini M. ;
Piccione E. ;
Quartararo P. ;
Ragni N. ;
Scagliola P. ;
Schönauer S. ;
Sismondi P. ;
Venturini P.L. ;
Volpe A. ;
Zullo F. .
BMC Women's Health, 9 (1)
[8]   Contraceptive compliance [J].
Dardano, KL ;
Burkman, RT .
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 2000, 27 (04) :933-+
[9]   Effects of the contraceptive patch, the vaginal ring and an oral contraceptive on APC resistance and SHBG: A cross-over study [J].
Fleischer, K. ;
van Vliet, H. A. ;
Rosendaal, F. R. ;
Rosing, J. ;
Tchaikovski, S. ;
Helmerhorst, F. M. .
THROMBOSIS RESEARCH, 2009, 123 (03) :429-435
[10]   Contraceptive failure rates: New estimates from the 1995 National Survey of Family Growth [J].
Fu, HS ;
Darroch, JE ;
Haas, T ;
Ranjit, N .
FAMILY PLANNING PERSPECTIVES, 1999, 31 (02) :56-63