Diastereoselective addition of chiral azomethine ylides to cinnamoyl moieties, attached to chiral auxiliaries

被引：23

作者：

Karlsson, S ^{[1
]}

Högberg, HE ^{[1
]}

机构：

[1] Mid Sweden Univ, Dept Nat & Environm Sci, SE-85170 Sundsvall, Sweden

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 14期

关键词：

D O I：

10.1016/S0957-4166(01)00366-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Doubly diastercoselective 1.3-dipolar cycloadditions of chiral azomethine ylides to cinnamoyl moieties, attached to chiral auxiliaries, were investigated. The resulting trans-3.4-disubstituted pyrrolidines were obtained in diastereomeric ratios of up to 78:22. The influence on this ratio by the constitution of the chiral ylide,vas found to be rather small. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1975 / 1976

页数：2

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