Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

被引：148
作者：
Feng, Simin [1 ]
Zhang, Xiaoli [2 ]
Shi, Dunyun [3 ]
Wang, Zheng [1 ]
机构：
[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin 300072, Peoples R China
[2] Shenzhen Univ, Shenzhen Peoples Hosp 2, Affiliated Hosp 1, Cent Lab,Hlth Sci Ctr, Shenzhen 518035, Peoples R China
[3] Shenzhen Univ, Shenzhen Peoples Hosp 2, Affiliated Hosp 1, Inst Hematol,Hlth Sci Ctr, Shenzhen 518035, Peoples R China
来源：
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING | 2021年 / 15卷 / 02期
关键词：
zeolitic imidazolate framework-8 (ZIF-8); synthesis methods; applications; drug delivery; METAL-ORGANIC-FRAMEWORK; ROOM-TEMPERATURE SYNTHESIS; ONE-POT SYNTHESIS; PHOTODYNAMIC THERAPY; INDOCYANINE GREEN; PHOTOTHERMAL THERAPY; SOLVOTHERMAL SYNTHESIS; GOLD NANOPARTICLES; THERANOSTIC AGENT; HYDROGEN STORAGE;
D O I：
10.1007/s11705-020-1927-8
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Zeolitic imidazolate framework-8 (ZIF-8), composed of Zn ions and imidazolate ligands, is a class of metal-organic frameworks, which possesses a similar structure as conventional aluminosilicate zeolites. This material exhibits inherent porous property, high loading capacity, and pH-sensitive degradation, as well as exceptional thermal and chemical stability. Extensive research effort has been devoted to relevant research aspects ranging from synthesis methods, property characterization to potential applications of ZIF-8. This review focuses on the recent development of ZIF-8 synthesis methods and its promising applications in drug delivery. The potential risks of using ZIF-8 for drug delivery are also summarized.
引用
收藏
页码：221 / 237
页数：17
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