Preservation of fertility in females with haematological malignancy

被引：85

作者：

Donnez, Jacques ^{[1
]}

Dolmans, Marie-Madeleine ^{[1
]}

机构：

[1] Clin Univ St Luc, Univ Catholique Louvain, Dept Gynecol, B-1200 Brussels, Belgium

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2011年 / 154卷 / 02期

关键词：

chemotherapy; cancer; fertility preservation; CRYOPRESERVED OVARIAN TISSUE; BONE-MARROW-TRANSPLANTATION; IMMATURE HUMAN OOCYTES; LONG-TERM SURVIVORS; HIGH-DOSE BUSULFAN; IN-VITRO; PRIMORDIAL FOLLICLES; CANCER-PATIENTS; HETEROTOPIC AUTOTRANSPLANTATION; PRESERVING FERTILITY;

D O I：

10.1111/j.1365-2141.2011.08723.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Several options are currently available for the preservation of fertility in cancer patients: embryo cryopreservation, oocyte cryopreservation or ovarian tissue cryopreservation. The choice of the most suitable strategy for preserving fertility depends on different parameters: the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status. Cryopreservation of ovarian tissue is the only option available for prepubertal girls and woman who cannot delay the start of chemotherapy. So far, 15 live births have been obtained after orthotopic transplantation of cryopreserved ovarian tissue.

引用

页码：175 / 184

页数：10

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