Treatment-refractory obsessive compulsive disorder

被引:23
作者
Atmaca, Murad [1 ]
机构
[1] Firat Univ, Sch Med, Dept Psychiat, Elazig, Turkey
关键词
OCD; Refractory; Treatment; Clinical aspects; TRANSCRANIAL MAGNETIC STIMULATION; DEEP BRAIN-STIMULATION; SEROTONIN REUPTAKE INHIBITOR; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; INTRAVENOUS CLOMIPRAMINE; RISPERIDONE AUGMENTATION; RILUZOLE AUGMENTATION; ANTERIOR CINGULOTOMY; ORBITOFRONTAL CORTEX;
D O I
10.1016/j.pnpbp.2015.12.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Obsessive compulsive disorder (OCD) is a chronic and debilitating disorder. As can be seen in other psychiatric disorders, refractoriness to treatment is an important problem for patients with OCD. OCD is a chronic disorder like collagen tissue disorders, with symptoms tending to wax and wane but rarely remitting spontaneously through the course of the disorder. An important part of OCD patients respond to serotonin reuptake inhibitors alone or in combination with other medications, and cognitive behavior therapy. However, up to 30%-40% of patients do not respond to the available treatment modalities. The present paper tried to review the current state of knowledge on definition, clinical aspects, etiopathogenesis, and treatment strategies of patients with refractory OCD. (C) 2015 Published by Elsevier Inc.
引用
收藏
页码:127 / 133
页数:7
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