Two new chiral nucleoside analogues:: (4R,5R)-4-(4,6-dimethylpyrimidin-2-ylsulfanyl)-5-[(2S,5R)-2-isopropyl-5-methylcyclohexyloxy]-2,3,4,5-tetrahydrofuran-2-one and (4R,5R)5-[(2S,5R)-isopropyl-5-methylcyclo-hexyloxy]-4-(4-methyl-1,3-thiazol-2-ylamino)-2,3,4,5-tetrahydrofuran-2-one

被引：1
|
作者：
He, L [1 ]
Liu, YM [1 ]
Zhang, W [1 ]
Chen, QH [1 ]
机构：
[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2005年 / 61卷
关键词：
D O I：
10.1107/S0108270105007833
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis and X- ray structural investigations have been carried out for the two title compounds, viz. C20H30N2O3S, ( I), and C18H28N2O3S, ( II). In both molecules, the cyclohexyloxy moiety and the conjugated cyclic system are located on opposite sides of the tetrahydrofuran- 2- one ring. In the crystal structure of ( II), there are two types of intermolecular hydrogen bonds, viz. C - H center dot center dot center dot S and N - H center dot center dot center dot O, and the molecules form a three- dimensional supramolecular architecture via the hydrogen bonds.
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收藏
页码：O390 / O392
页数：3
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