Bupropion SR and contingency management for adolescent smoking cessation

被引：51

作者：

Gray, Kevin M. ^{[1
]}

Carpenter, Matthew J. ^{[1
,2
]}

Baker, Nathaniel L. ^{[3
]}

Hartwell, Karen J. ^{[1
]}

Lewis, A. Lee ^{[1
]}

Hiott, D. Walter ^{[1
]}

Deas, Deborah ^{[1
]}

Upadhyaya, Himanshu P. ^{[1
]}

机构：

[1] MUSC, Dept Psychiat & Behav Sci, Charleston, SC USA

[2] MUSC, Hollings Canc Ctr, Charleston, SC USA

[3] MUSC, Dept Med, Charleston, SC USA

来源：

JOURNAL OF SUBSTANCE ABUSE TREATMENT | 2011年 / 40卷 / 01期

关键词：

Bupropion; Contingency management; Nicotine; Smoking; Tobacco; Adolescent; Youth; Treatment; RANDOMIZED CLINICAL-TRIAL; CIGARETTE-SMOKING; NICOTINE DEPENDENCE; PLASMA-COTININE; CARBON-MONOXIDE; FAGERSTROM TEST; SMOKERS; ABSTINENCE; THERAPY; TOBACCO;

D O I：

10.1016/j.jsat.2010.08.010

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

There is a significant need for evidence-based treatments for adolescent smoking cessation. Prior research, although limited, has suggested potential roles for bupropion sustained-release (SR) and contingency management (CM), but no previous studies have assessed their combined effect. In a double-blind, placebo-controlled design, 134 adolescent smokers were randomized to receive a 6-week course of bupropion SR + CM, bupropion SR + non-CM, placebo + CM, or placebo + non-CM, with final follow-up at 12 weeks. The primary outcome was 7-day cotinine-verified point prevalence abstinence, allowing for a 2-week grace period. Combined bupropion SR + CM treatment yielded significantly superior abstinence rates during active treatment when compared with placebo + non-CM treatment. In addition, combined treatment showed greater efficacy at multiple time points than did either bupropion SR + non-CM or placebo + CM treatment. Combined bupropion SR and CM appears efficacious, at least in the short-term, for adolescent smoking cessation and may be superior to either intervention alone. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：77 / 86

页数：10

共 46 条

[1]

[Anonymous], 2007, An introduction to categorical data analysis

[2]

[Anonymous], 2000, Reducing tobacco use: A report of the surgeon general

[3]

Backinger CL, 2003, TOB CONTROL, V12, P46

[4]

Budney A.J., 1998, A community reinforcement plus voucher Approach