PRIMARY APPLICATION OF MICRO-FLOW IMAGING TECHNOLOGY IN THE DIAGNOSIS OF HEPATIC TUMORS

被引:28
作者
Han, Hong [1 ]
Ding, Hong [1 ]
Ji, Zhengbiao [1 ]
Zhang, Weibin [1 ]
Wang, Qun [1 ]
Wang, Wenping [1 ]
机构
[1] Fudan Univ, Zhongshan Hosp, Shanghai Inst Med Imaging, Dept Ultrasound, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
Ultrasound; Micro-flow imaging; Liver; Tumor; CONTRAST-ENHANCED ULTRASOUND; FOCAL NODULAR HYPERPLASIA; ENDOTHELIAL GROWTH-FACTOR; MICROVESSEL DENSITY; VASCULAR INVASION; BREAST CANCERS; LIVER;
D O I
10.1016/j.ultrasmedbio.2018.09.025
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The purpose of the study was to evaluate the vascular architecture of focal liver lesions with the newly released non-contrast micro-flow imaging (MFI) technique. Eighty patients with 80 hepatic tumors were enrolled in this study. The richness of displayed blood flow was first compared with color Doppler flow imaging using grades according to Adler's method. The results indicated that MFI outperformed color Doppler flow imaging with a statistically significant difference (p < 0.0001). With the enhanced position in arterial phase of contrast-enhanced ultrasound imaging as the ground truth, the displayed blood flow distribution within tumors in MFI was further evaluated. The coincidence rate between MFI and contrast-enhanced ultrasound was 73.75% (59/80), which was higher than that of color Doppler flow imaging (52.5%, 42/80) (p < 0.0001). Moreover, for the five cases of focal nodular hyperplasia, MFI clearly revealed the spoke-wheel or radiating intra-tumoral vasculature, a finding specific to the diagnosis of focal nodular hyperplasia. (C) 2018 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:395 / 401
页数:7
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