Fetal arrhythmia caused by dysregulation of HERG channels

被引:3
作者
Grunnet, Morten [1 ]
机构
[1] Univ Copenhagen, Dept Biomed Sci, Danish Natl Res Fdn, Ctr Cardiac Arrhythmia, DK-2200 Copenhagen N, Denmark
关键词
D O I
10.1016/j.hrthm.2008.02.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:562 / 564
页数:3
相关论文
共 21 条
[1]   MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia [J].
Abbott, GW ;
Sesti, F ;
Splawski, I ;
Buck, ME ;
Lehmann, WH ;
Timothy, KW ;
Keating, MT ;
Goldstein, SAN .
CELL, 1999, 97 (02) :175-187
[2]   Transmural dispersion of repolarization and arrhythmogenicity - The Brugada syndrome versus the long QT syndrome [J].
Antzelevitch, C ;
Yan, GX ;
Shimizu, W .
JOURNAL OF ELECTROCARDIOLOGY, 1999, 32 :158-165
[3]   Recurrent intrauterine fetal loss due to near absence of HERG: Clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation [J].
Bhuiyan, Zahurul A. ;
Momenah, Tarek S. ;
Gong, Qiuming ;
Amin, Ahmad S. ;
Ghamdi, Saleh Al ;
Carvalho, Julene S. ;
Homfray, Tessa ;
Mannens, Marcel M. A. M. ;
Zhou, Zhengfeng ;
Wilde, Arthur A. M. .
HEART RHYTHM, 2008, 5 (04) :553-561
[4]   C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3ε [J].
Choe, Chi-un ;
Schulze-Bahr, Eric ;
Neu, Axel ;
Xu, Jun ;
Zhu, Zheng I. ;
Sauter, Kathrin ;
Bahring, Robert ;
Priori, Silvia ;
Guicheney, Pascale ;
Monnig, Gerold ;
Neapolitano, Carlo ;
Heidemann, Jan ;
Clancy, Colleen E. ;
Pongs, Olaf ;
Isbrandt, Dirk .
HUMAN MOLECULAR GENETICS, 2006, 15 (19) :2888-2902
[5]   Prolonged QT interval predicts cardiac and all-cause mortality in the elderly - The Rotterdam study [J].
de Bruyne, MC ;
Hoes, AW ;
Kors, JA ;
Hofman, A ;
van Bemmel, JH ;
Grobbee, DE .
EUROPEAN HEART JOURNAL, 1999, 20 (04) :278-284
[6]   Nonsense-mediated mRNA decay in health and disease [J].
Frischmeyer, PA ;
Dietz, HC .
HUMAN MOLECULAR GENETICS, 1999, 8 (10) :1893-1900
[7]   Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome [J].
Gong, Qiuming ;
Zhang, Li ;
Vincent, G. Michael ;
Horne, Benjamin D. ;
Zhou, Zhengfeng .
CIRCULATION, 2007, 116 (01) :17-24
[8]   Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623[N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N′-(3′-trifluoromethylphenyl)urea] [J].
Hansen, Rie Schultz ;
Diness, Thomas Goldin ;
Christ, Torsten ;
Wettwer, Erich ;
Ravens, Ursula ;
Olesen, Soren-Peter ;
Grunnet, Morten .
MOLECULAR PHARMACOLOGY, 2006, 70 (04) :1319-1329
[9]   Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) [J].
Hansen, RS ;
Diness, TG ;
Christ, T ;
Demnitz, J ;
Ravens, U ;
Olesen, SP ;
Grunnet, M .
MOLECULAR PHARMACOLOGY, 2006, 69 (01) :266-277
[10]   Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia [J].
Hondeghem, LM ;
Dujardin, K ;
De Clerck, F .
CARDIOVASCULAR RESEARCH, 2001, 50 (02) :345-353