Rhenium-Catalyzed Regio- and Stereoselective Addition of Two Carbon Units to Terminal Alkynes via Carbon-Carbon Bond Cleavage of β-Keto Sulfones

被引：38

作者：

Kuninobu, Yoichiro ^{[1
]}

Matsuzaki, Hironori ^{[1
]}

Nishi, Mitsumi ^{[1
]}

Takai, Kazuhiko ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Nat Sci & Technol, Div Chem & Biochem, Kita Ku, Okayama 7008530, Japan

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 11期

关键词：

SINGLE-BOND; INSERTION; CYCLOBUTENONES; CYCLOBUTANONES; 2-PYRANONES; ACETYLENES; PHENOLS; ESTERS;

D O I：

10.1021/ol2008507

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of beta-keto sulfones with terminal alkynes gave unsaturated delta-keto sulfones in good to excellent yields under rhenium catalysis. In this reaction, the insertion of the alkynes into the nonstrained carbon-carbon single bond between the alpha- and beta-positions of the beta-keto sulfones proceeded smoothly, and (Z)-isomers were produced with high regio- and stereoselectivities.

引用

页码：2959 / 2961

页数：3

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