Long-acting buprenorphine vs. naltrexone opioid treatments in CJS']JS-involved adults (EXIT-CJS']JS)

被引：15

作者：

Waddell, Elizabeth Needham ^{[1
,2
]}

Springer, Sandra A. ^{[3
]}

Marsch, Lisa A. ^{[3
]}

Farabee, David ^{[4
]}

Schwartz, Robert P. ^{[5
]}

Nyaku, Amesika ^{[6
]}

Reeves, Rusty ^{[7
]}

Goldfeld, Keith ^{[4
]}

McDonald, Ryan D. ^{[4
]}

Malone, Mia ^{[5
]}

Cheng, Anna ^{[5
]}

Saunders, Elizabeth C. ^{[3
]}

Monico, Laura ^{[5
]}

Gryczynski, Jan ^{[5
]}

Bell, Kathleen ^{[3
]}

Harding, Kasey ^{[8
]}

Violette, Sandra ^{[9
]}

Groblewski, Thomas ^{[10
]}

Martin, Wendy ^{[11
]}

Talon, Kasey ^{[11
]}

Beckwith, Nicole ^{[11
]}

Suchocki, Andrew ^{[12
]}

Torralva, Randy ^{[13
]}

Wisdom, Jennifer P. ^{[13
]}

Lee, Joshua D. ^{[4
]}

机构：

[1] Oregon Hlth & Sci Univ, Sch Publ Hlth, Portland, OR 97201 USA

[2] Oregon Hlth & Sci Univ, OHSU Sch Med, Portland, OR 97201 USA

[3] Dartmouth Coll, Hanover, NH 03755 USA

[4] NYU Grossman SOM, New York, NY 10016 USA

[5] Friends Res Inst, Hollywood, CA USA

[6] State Univ New Jersey, New Jersey Med Sch, New Brunswick, NJ USA

[7] Rutgers Univ Correct Hlth Care, Rutgers Robert Wood Johnson Med Sch, New Brunswick, NJ USA

[8] Community Hlth Ctr Inc, Middletown, CT USA

[9] Connecticut Dept Correct, Wethersfield, CT USA

[10] New Hampshire Dept Correct, Concord, NH USA

[11] RD Better Life, Somersworth, NH USA

[12] Clackamas Cty Hlth Ctr, Sunnyside, OR USA

[13] CODA Inc, Portland, OR USA

来源：

JOURNAL OF SUBSTANCE ABUSE TREATMENT | 2021年 / 128卷

关键词：

Opioid use disorder; Medication treatment; Buprenorphine; Naltrexone; Injection; Criminal justice; EXTENDED-RELEASE NALTREXONE; ABUSE TREATMENT; DOUBLE-BLIND; NALOXONE; INCARCERATION; MULTICENTER; DEPENDENCE; RELAPSE; HIV;

D O I：

10.1016/j.jsat.2021.108389

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

The EXIT-CJS (N = 1005) multisite open-label randomized controlled trial will compare retention and effectiveness of extended-release buprenorphine (XR-B) vs. extended-release naltrexone (XR-NTX) to treat opioid use disorder (OUD) among criminal justice system (CJS)-involved adults in six U.S. locales (New Jersey, New York City, Delaware, Oregon, Connecticut, and New Hampshire). With a pragmatic, noninferiority design, this study hypothesizes that XR-B (n = 335) will be noninferior to XR-NTX (n = 335) in retention-in-study-medication treatment (the primary outcome), self-reported opioid use, opioid-positive urine samples, opioid overdose events, and CJS recidivism. In addition, persons with OUD not eligible or interested in the RCT will be recruited into an enhanced treatment as usual arm (n = 335) to examine usual care outcomes in a quasi-experimental observational cohort.

引用

页数：8

共 1 条

[1] Comparison of the characteristics of patients treated with sublingual vs. long-acting injectable buprenorphine formulations for treatment of opioid use disorder: A retrospective cohort study
Nayer, Carmen
Sveticic, Jerneja
Abeysundera, Hesitha
Bui, Tuan Anh
AUSTRALASIAN PSYCHIATRY, 2022, 30 (06) : 754 - 758

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