The COVID-19 vaccine ChAdOx1-S is not contaminated with sulfated glycosaminoglycans

被引:5
作者
Alban, Susanne [1 ]
Neupane, Sandesh [1 ]
Girreser, Ulrich [2 ]
Soennichsen, Frank D. [3 ]
Greinacher, Andreas [4 ]
机构
[1] Christian Albrechts Univ Kiel, Inst Pharmazeut, Abt Pharmazeut Biol, Kiel, Germany
[2] Christian Albrechts Univ Kiel, Inst Pharmazeut, Abt Pharmazeut Chem, Kiel, Germany
[3] Christian Albrechts Univ Kiel, Otto Diels Inst Organ Chem, Kiel, Germany
[4] Univ Med Greifswald, Inst Transfus Med, Greifswald, Germany
关键词
COMPLEXES;
D O I
10.1111/jth.15633
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:777 / 780
页数:4
相关论文
共 16 条
  • [1] Alban S., 2012, HEPARIN INDUCED THRO, V5th, P181
  • [2] Comparison of established and novel purity tests for the quality control of heparin by means of a set of 177 heparin samples
    Alban, Susanne
    Luehn, Susanne
    Schiemann, Simone
    Beyer, Tanja
    Norwig, Jochen
    Schilling, Claudia
    Raedler, Oliver
    Wolf, Bernhard
    Matz, Magnus
    Baumann, Knut
    Holzgrabe, Ulrike
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2011, 399 (02) : 605 - 620
  • [3] ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome
    Baker, Alexander T.
    Boyd, Ryan J.
    Sarkar, Daipayan
    Teijeira-Crespo, Alicia
    Chan, Chun Kit
    Bates, Emily
    Waraich, Kasim
    Vant, John
    Wilson, Eric
    Truong, Chloe D.
    Lipka-Lloyd, Magdalena
    Fromme, Petra
    Vermaas, Josh
    Williams, Dewight
    Machiesky, LeeAnn
    Heurich, Meike
    Nagalo, Bolni M.
    Coughlan, Lynda
    Umlauf, Scott
    Chiu, Po-Lin
    Rizkallah, Pierre J.
    Cohen, Taylor S.
    Parker, Alan L.
    Singharoy, Abhishek
    Borad, Mitesh J.
    [J]. SCIENCE ADVANCES, 2021, 7 (49):
  • [4] Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria
    Brandt, Sven
    Krauel, Krystin
    Jaax, Miriam
    Renne, Thomas
    Helm, Christiane A.
    Hammerschmidt, Sven
    Delcea, Mihaela
    Greinacher, Andreas
    [J]. THROMBOSIS AND HAEMOSTASIS, 2015, 114 (06) : 1189 - 1198
  • [5] Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia
    Cines, Douglas B.
    Yarovoi, Serge V.
    Zaitsev, Sergei V.
    Lebedeva, Tatiana
    Rauova, Lubica
    Poncz, Mortimer
    Arepally, Gowthami M.
    Khandelwal, Sanjay
    Stepanova, Victoria
    Rux, Ann H.
    Cuker, Adam
    Guo, Cecilia
    Ocariza, Linnette Mae
    Travers, Richard J.
    Smith, Stephanie A.
    Kim, Hugh
    Morrissey, James H.
    Conway, Edward M.
    [J]. BLOOD ADVANCES, 2016, 1 (01) : 62 - 74
  • [6] EMA, COVID 19 VACC SAF UP
  • [7] European Medicines Agency (EMA), EMA949072021 EPAR
  • [8] Autoimmune heparin-induced thrombocytopenia
    Greinacher, A.
    Selleng, K.
    Warkentin, T. . E.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2017, 15 (11) : 2099 - 2114
  • [9] Greinacher A., 2021, UNDERSTANDING CHADOX, DOI [10.21203/rs.3.rs-440461/v1, DOI 10.21203/RS.3.RS-440461/V1]
  • [10] Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination
    Greinacher, Andreas
    Thiele, Thomas
    Warkentin, Theodore E.
    Weisser, Karin
    Kyrle, Paul A.
    Eichinger, Sabine
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (22) : 2092 - 2101