Evaluation of green synthesized silver nanoparticles against parasites

被引：214

作者：

Marimuthu, Sampath ^{[1
]}

Rahuman, Abdul Abdul ^{[1
]}

Rajakumar, Govindasamy ^{[1
]}

Santhoshkumar, Thirunavukkarasu ^{[1
]}

Kirthi, Arivarasan Vishnu ^{[1
]}

Jayaseelan, Chidambaram ^{[1
]}

Bagavan, Asokan ^{[1
]}

Zahir, Abdul Abduz ^{[1
]}

Elango, Gandhi ^{[1
]}

Kamaraj, Chinnaperumal ^{[1
]}

机构：

[1] C Abdul Hakeem Coll, Unit Nanotechnol & Bioact Nat Prod, Post Grad & Res Dept Zool, Melvisharam 632509, Tamil Nadu, India

来源：

PARASITOLOGY RESEARCH | 2011年 / 108卷 / 06期

关键词：

MEDICINAL-PLANT EXTRACTS; ESSENTIAL OILS; CATTLE TICK; ANOPHELES; DIPTERA; LARVAE; TOXICITY; AEDES; ECOTOXICITY; LEGUMINOSAE;

D O I：

10.1007/s00436-010-2212-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Green nanoparticle synthesis has been achieved using environmentally acceptable plant extract and eco-friendly reducing and capping agents. The present study was based on assessments of the antiparasitic activities to determine the efficacies of synthesized silver nanoparticles (AgNPs) using aqueous leaf extract of Mimosa pudica Gaertn (Mimosaceae) against the larvae of malaria vector, Anopheles subpictus Grassi, filariasis vector Culex quinquefasciatus Say (Diptera: Culicidae), and Rhipicephalus (Boophilus) microplus Canestrini (Acari: Ixodidae). Parasite larvae were exposed to varying concentrations of aqueous extract of M. pudica and synthesized AgNPs for 24 h. AgNPs were rapidly synthesized using the leaf extract of M. pudica and the formation of nanoparticles was observed within 6 h. The results recorded from UV-vis spectrum, Fourier transform infrared, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy support the biosynthesis and characterization of AgNPs. The maximum efficacy was observed in synthesized AgNPs against the larvae of A. subpictus, C. quinquefasciatus, and R. microplus (LC50 = 13.90, 11.73, and 8.98 mg/L, r (2) = 0.411, 0.286, and 0.479), respectively. This is the first report on antiparasitic activity of the plant extract and synthesized AgNPs.

引用

页码：1541 / 1549

页数：9

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