Uncaria tomentosa and acute ischemic kidney injury in rats

被引：0
作者：
Fernandes Vattimo, NMaria de Fatima [1 ]
da Silva, Natalia Oliveira [1 ]
机构：
[1] Univ Sao Paulo, Sch Nursing, Sao Paulo, Brazil
来源：
REVISTA DA ESCOLA DE ENFERMAGEM DA USP | 2011年 / 45卷 / 01期
关键词：
Cat's claw; Kidney; Therapeutics; Rats; ACUTE-RENAL-FAILURE;
D O I：
暂无
中图分类号：
R47 [护理学];
学科分类号：
1011 ;
摘要：
The objective of this study was to evaluate the renoprotective effects of Uncaria Tomentosa (cat's claw) on ischemic acute kidney injury induced by renal clamping in rats. The hypoxia and hypoperfusion increase the production of reactive species already present in the inflammatory process. Results showed that the renal function evaluated by creatinine clearance, the urinary excretion of peroxides and malondealdehyde indexes demonstrated that UT induced renoprotection, probably related to its antioxidant activities.
引用
收藏
页码：189 / 193
页数：5
相关论文
共 21 条
[1]  
AMEND WJC, 1985, UROLOGIA GERAL, P433
[2]  
Bezerra JS, 2008, J BRAS NEFROL, V30, P99
[3]  
BRADY HR, 2007, BRENNER RECTORS KIDN, P1201
[4]  
CARVALHO JCT, 2004, FITOTERAPICOS ANTIIN, P423
[5]   NEW QUINOVIC ACID GLYCOSIDES FROM UNCARIA-TOMENTOSA [J].
CERRI, R ;
AQUINO, R ;
DESIMONE, F ;
PIZZA, C .
JOURNAL OF NATURAL PRODUCTS, 1988, 51 (02) :257-261
[6]   Establishing biomarkers of oxidative stress: The measurement of hydrogen peroxide in human urine [J].
Halliwell, B ;
Lee, HL ;
Yee, TP ;
Lim, S ;
Kelly, R .
CURRENT MEDICINAL CHEMISTRY, 2004, 11 (09) :1085-1092
[7]  
Keplinger K, 1999, J ETHNOPHARMACOL, V64, P23, DOI 10.1016/S0378-8741(98)00096-8
[8]  
Lima ES, 2001, Revista Brasileira de Ci@ncias Farmac@uticas, V37, P293
[9]  
MIGUEL MD, 2004, DESENVOLVIMENTO FITO, P18
[10]  
Oliveira V C, 2001, Rev Esc Enferm USP, V35, P200
123