COVID-19 Co-infection in a patient with Crimean Congo Hemorrhagic Fever: A Case Report

被引:11
作者
Buyuktuna, Seyit Ali [1 ]
Hasbek, Mursit [2 ]
Oksuz, Caner [1 ]
Baysal, Cihad [1 ]
Oz, Murtaza [1 ]
Elaldi, Nazif [1 ]
Bakir, Mehmet [1 ]
机构
[1] Sivas Cumhuriyet Univ, Dept Infect Dis & Clin Microbiol, Fac Med, Sivas, Turkey
[2] Sivas Cumhuriyet Univ, Dept Med Microbiol, Fac Med, Sivas, Turkey
来源
MIKROBIYOLOJI BULTENI | 2021年 / 55卷 / 03期
关键词
Co-infection; COVID-19; CCHF; EFFICACY; PARAMETERS; RIBAVIRIN;
D O I
10.5578/mb.20219813
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Crimean-Congo Hemorrhagic Fever (CCHF) is an acute viral zoonotic disease. Coronavirus disease-2019 (COVID-19) is a newly emerging viral disease and it is caused by "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)". In this article, a case diagnosed with CCHF and COVID-19 coinfection confirmed by the polymerase chain reaction (PCR) method and its management was presented. A thirty-five years old female patient admitted to the hospital with the complaint of fever for one day and common body pain. It was learned that three days before the onset of her complaints, she removed a tick adhering to the anterior abdominal wall with no precaution. Her body temperature was 38 degrees C degrees and her respiratory rate was 22 per minute. The leucocyte count was 3660/mm(3) and the platelet count was 138.000/mm(3). It was determined that prothrombin time was 15.4 seconds, international normalized ratio (INR) was 1.35 seconds, and D-dimer level was 1310 ng/ml. The patient was hospitalized with prediagnosis of CCHF. Supportive treatment was started. On the second day at the clinical follow-up of the patient, complaints of sore throat and cough without sputum started. A combined nasopharyngeal and throat swab sample was taken from the patient because of the suspicion of COVID-19. COVID-19 PCR test result was reported as positive. Favipiravir treatment was started. The CCHF-PCR test, which was studied from the serum sample sent to the Microbiology Reference Laboratories was reported as positive. From the third day of favipiravir treatment; the patient did not have a fever and her complaints regressed. On the ninth day of her hospitalization, she was discharged. In this case; it is important to show that both diseases, especially in regions where CCHF disease is endemic, can be confused due to the similarity of the clinical picture with COVID-19 and to know that they can coexist.
引用
收藏
页码:445 / 451
页数:7
相关论文
共 20 条
[1]   Taxonomy of the order Bunyavirales: update 2019 [J].
Abudurexiti, Abulikemu ;
Adkins, Scott ;
Alioto, Daniela ;
Alkhovsky, Sergey V. ;
Avsic-Zupanc, Tatjana ;
Ballinger, Matthew J. ;
Bente, Dennis A. ;
Beer, Martin ;
Bergeron, Eric ;
Blair, Carol D. ;
Briese, Thomas ;
Buchmeier, Michael J. ;
Burt, Felicity J. ;
Calisher, Charles H. ;
Chang, Chenchen ;
Charrel, Remi N. ;
Choi, Il Ryong ;
Clegg, J. Christopher S. ;
de la Torre, Juan Carlos ;
de Lamballerie, Xavier ;
Deng, Fei ;
Di Serio, Francesco ;
Digiaro, Michele ;
Drebot, Michael A. ;
Duan, Xiaomei ;
Ebihara, Hideki ;
Elbeaino, Toufic ;
Ergunay, Koray ;
Fulhorst, Charles F. ;
Garrison, Aura R. ;
Gao, George Fu ;
Gonzalez, Jean-Paul J. ;
Groschup, Martin H. ;
Guenther, Stephan ;
Haenni, Anne-Lise ;
Hall, Roy A. ;
Hepojoki, Jussi ;
Hewson, Roger ;
Hu, Zhihong ;
Hughes, Holly R. ;
Jonson, Miranda Gilda ;
Junglen, Sandra ;
Klempa, Boris ;
Klingstrom, Jonas ;
Kou, Chun ;
Laenen, Lies ;
Lambert, Amy J. ;
Langevin, Stanley A. ;
Liu, Dan ;
Lukashevich, Igor S. .
ARCHIVES OF VIROLOGY, 2019, 164 (07) :1949-1965
[2]  
[Anonymous], 2021, COVID 19 SARS COV 2 COVID 19 SARS COV 2
[3]   Identification of the crucial parameters regarding the efficacy of ribavirin therapy in Crimean-Congo haemorrhagic fever (CCHF) patients: a systematic review and meta-analysis [J].
Arab-Bafrani, Zahra ;
Jabbari, Ali ;
Hashemi, Mohammad Mostakhdem ;
Arabzadeh, Ali Mohammad ;
Gilanipour, Atena ;
Mousavi, Elham .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2019, 74 (12) :3432-3439
[4]   Validation of a severity grading score (SGS) system for predicting the course of disease and mortality in patients with Crimean-Congo hemorrhagic fever (CCHF) [J].
Bakir, M. ;
Gozel, M. G. ;
Koksal, I. ;
Asik, Z. ;
Gunal, O. ;
Yilmaz, H. ;
But, A. ;
Yilmaz, G. ;
Engin, A. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2015, 34 (02) :325-330
[5]   Outcome of noncritical COVID-19 patients with early hospitalization and early antiviral treatment outside the ICU [J].
Calik Basaran, Nursel ;
Uyaroglu, Oguz Abdullah ;
Telli Dizman, Gulcin ;
Ozisik, Lale ;
Sahin, Taha Koray ;
Tas, Zahit ;
Inkaya, Ahmet Cagkan ;
Karahan, Sevilay ;
Sehnaz, A. L. P. ;
Alpaslan, A. L. P. ;
Metan, Gokhan ;
Zarakolu, Pinar ;
Sain Guven, Gulay ;
Oz, Serife Gul ;
Topeli, Arzu ;
Uzun, Omrum ;
Akova, Murat ;
Unal, Serhat .
TURKISH JOURNAL OF MEDICAL SCIENCES, 2021, 51 (02) :411-420
[6]   COVID-19: to be or not to be; that is the diagnostic question [J].
Coleman, Jamie J. ;
Manavi, Kaveh ;
Marson, Ella J. ;
Botkai, Adam H. ;
Sapey, Elizabeth .
POSTGRADUATE MEDICAL JOURNAL, 2020, 96 (1137) :392-398
[7]   COVID-19 co-infection in a patient with brucella bacteremia [J].
Elzein, Fatehi ;
Alsherbeeni, Nisreen ;
Almatrafi, Kholoud ;
Shosha, Diaa ;
Naoufel, Kaabia .
RESPIRATORY MEDICINE CASE REPORTS, 2020, 31
[8]   Crimean-Congo haemorrhagic fever [J].
Ergönül, Ö .
LANCET INFECTIOUS DISEASES, 2006, 6 (04) :203-214
[9]   The efficacy of oral ribavirin on clinical and laboratory parameters in Crimean-Congo hemorrhagic fever: an observational study from Turkey [J].
Ertem, Gunay ;
Sonmezer, Meliha Cagla ;
Temocin, Fatih ;
Ataman Hatipoglu, Cigdem ;
Tulek, Necla ;
Oral, Behic .
TURKISH JOURNAL OF MEDICAL SCIENCES, 2016, 46 (05) :1407-1414
[10]   Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques [J].
Hawman, David W. ;
Haddock, Elaine ;
Meade-White, Kimberly ;
Nardone, Glenn ;
Feldmann, Friederike ;
Hanley, Patrick W. ;
Lovaglio, Jamie ;
Scott, Dana ;
Komeno, Takashi ;
Nakajima, Nozomi ;
Furuta, Yousuke ;
Gowen, Brian B. ;
Feldmann, Heinz .
ANTIVIRAL RESEARCH, 2020, 181