Advances in Pediatric Fatty Liver Disease Pathogenesis, Diagnosis, and Treatment

被引：11

作者：

Braun, Hayley A. ^{[1
]}

Faasse, Sarah A. ^{[1
,2
]}

Vos, Miriam B. ^{[1
,2
]}

机构：

[1] Emory Univ, Sch Med, Dept Pediat, Div Gastroenterol Hepatol & Nutr, 1760 Haygood Dr North East, Atlanta, GA 30322 USA

[2] Childrens Healthcare Atlanta, Div Gastroenterol Hepatol & Nutr, 1405 Clifton Rd, Atlanta, GA 30329 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2018年 / 47卷 / 04期

关键词：

Pediatric NAFLD; Review; Treatment; Type II diabetes; Diagnosis; MAGNETIC-RESONANCE-SPECTROSCOPY; DE-NOVO LIPOGENESIS; VITAMIN-E TREATMENT; GROWTH-FACTOR; 21; INSULIN-RESISTANCE; NONALCOHOLIC STEATOHEPATITIS; FIBROSIS PREDICTION; HEPATIC STEATOSIS; OBESE ADOLESCENTS; INTRAHEPATIC FAT;

D O I：

10.1016/j.gtc.2018.07.016

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Pediatric nonalcoholic fatty liver disease is an increasingly prevalent disease, but its pathophysiology is not fully elucidated, diagnosis is difficult and invasive, and therapeutic options are limited. This article addresses the recent advancements made in understanding the pathophysiology of nonalcoholic fatty liver disease, the development of less invasive diagnostic modalities, and emerging therapeutic options, including ongoing clinical trials in children.

引用

页码：949 / 968

页数：20

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