Highly stereoselective and catalyst-free synthesis of annulated tetrahydropyridines by intramolecular imino-Diels-Alder reaction under microwave irradiation in water

被引：15

作者：

Lezana, Nicolas ^{[1
]}

Matus-Perez, Massiel ^{[1
]}

Galdamez, Antonio ^{[1
]}

Luehr, Susan ^{[2
]}

Vilches-Herrer, Marcelo ^{[1
]}

机构：

[1] Univ Chile, Fac Sci, Dept Chem, Las Palmeras 3425, Santiago 7800024, Chile

[2] Univ Santiago Chile, Fac Chem & Biol, Dept Mat Sci, Av Libertador Bernardo OHiggins 3363, Santiago 9170022, Chile

来源：

GREEN CHEMISTRY | 2016年 / 18卷 / 13期

关键词：

ONE-POT; N-ARYLIMINES; 1-AZA-1,3-BUTADIENE; DERIVATIVES; ALDEHYDES; MECHANISM;

D O I：

10.1039/c6gc00912c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A microwave-assisted method for the synthesis of tetracyclic tetra-hydropyridines via an intramolecular imino-Diels-Alder reaction in water is reported. The reaction proceeds under catalyst-free conditions and shows excellent stereoselectivity.

引用

页码：3712 / 3717

页数：6

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