Copper-Catalyzed Olefin Aminoacetoxylation

被引：72

作者：

Mancheno, Danny E. ^{[1
]}

Thornton, Aaron R. ^{[1
]}

Stoll, Armin H. ^{[1
]}

Kong, Aidi ^{[1
]}

Blakey, Simon B. ^{[1
]}

机构：

[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 18期

关键词：

INTRAMOLECULAR AMINOOXYGENATION; ASYMMETRIC AMINOHYDROXYLATION; ORGANIC-SYNTHESIS; BOND FORMATION; ALKENES; PALLADIUM; ACTIVATION; COMPLEXES;

D O I：

10.1021/ol101702w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new catalyst system for intramolecular olefin aminoacetoxylation is described. In contrast to previously reported palladium- and copper-catalyzed systems, the conditions outlined in this communication favor piperdine formation with terminal olefin substrates and induce cyclization with traditionally less reactive disubstituted olefins.

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页码：4110 / 4113

页数：4

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