Synthesis of Cyclic Imides from Simple Diols

被引：103

作者：

Zhang, Jian ^{[1
]}

Senthilkumar, Muthaiah ^{[1
]}

Ghosh, Subhash Chandra ^{[1
]}

Hong, Soon Hyeok ^{[1
]}

机构：

[1] Nanyang Technol Univ, Div Chem & Biol Chem, 21 Nanyang Link,SPMS CBC-06-21, Singapore 637371, Singapore

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 36期

基金：

新加坡国家研究基金会;

关键词：

diols; homogeneous catalysis; imides; N-heterocyclic carbenes; ruthenium; DIRECT AMIDE SYNTHESIS; ARYL BORONIC ACIDS; CATALYZED CARBONYLATION; EFFICIENT SYNTHESIS; RING EXPANSION; LEWIS-ACID; ALCOHOLS; AMINES; ESTERS; ALDEHYDES;

D O I：

10.1002/anie.201002136

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

There's something imide so strong: Cyclic imides were synthesized from simple diols with primary amines in a single step using an in-situ-generated ruthenium catalytic system. The atom-economical and operatively simple syntheses of succinimides, phthalimides, and glutarimides, which are important building blocks in natural products and drugs, was also demonstrated. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6391 / 6395

页数：5

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