Genetic factors in the genesis of Alzheimer's disease

被引：0
|
作者：
St George-Hyslop, PH
机构：
[1] Univ Toronto, Ctr Res Neurodegenerat Dis, Dept Med, Toronto, ON M5S 3H2, Canada
[2] Univ Hlth Network, Div Neurol, Dept Med, Toronto, ON M5S 3H2, Canada
来源：
ALZEHEIMER'S DISEASE: A COMPENDIUM OF CURRENT THEORIES | 2000年 / 924卷
关键词：
AD susceptibility genes; amyloid-beta hypothesis; tau protein mutations; APOE; inheritance of AD; familial AD;
D O I：
暂无
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
At least four different genes have been identified that are associated with inherited susceptibiltiy to Alzheimer's disease. Some of the genes are highly penetrant (PS1, PS2, beta APP); the other, APOE, is a weaker susceptibility factor. Several additional genes are suspected to exist but have not yet been cloned.
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页码：1 / 7
页数：7
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