Allogeneic haematopoietic cell transplantation for diffuse large B cell lymphoma: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)

被引:2
作者
Gauthier, Jordan [1 ,2 ,8 ]
Chantepie, Sylvain [3 ,8 ]
Bouabdallah, Krimo [4 ,8 ]
Jost, Edgar [5 ,8 ]
Nguyen, Stephanie [6 ,8 ]
Gac, Anne-Claire [3 ,8 ]
Damaj, Gandhi [3 ,8 ]
Dulery, Remy [5 ,8 ]
Michallet, Mauricette [7 ,8 ]
Delage, Jeremy [8 ,9 ]
Lewalle, Philippe [8 ,10 ]
Morschhauser, Franck [2 ,8 ]
Salles, Gilles [8 ]
Yakoub-Agha, Ibrahim [8 ,11 ]
Cornillon, Jerome [8 ]
机构
[1] CHRU Lille, Pole Specialtes Med & Gerontol Secteur Allogre Ce, F-59037 Lille, France
[2] Univ Lille, UFR Med, F-59000 Lille, France
[3] Hop La Pitie Salpetrisre, AP HP, Paris, France
[4] CHU Caen, Serv Hematol, Caen, France
[5] Hop St Antoine, AP HP, Serv Hematol, Paris, France
[6] CHU Lyon, Serv Hematol, Lyon, France
[7] Univ Klinikum Aachen, Klin Onkol Hamatol & Stammzelltransplantat, Aachen, Germany
[8] CHU Montpellier, Serv Hematol, Montpellier, France
[9] Univ Libre Bruxelles, Inst Jules Bordet, Serv Hematol, Brussels, Belgium
[10] Univ Lille 2, CHU Lille, LIRIC Inserm U995, F-59000 Lille, France
[11] Inst Cancerol Lucien Neuwirth, Dept Hematol Clin, St Priest En Jarez, France
关键词
Allogeneic stem cell; transplantation; Lymphoma; Guidelines; NON-HODGKIN-LYMPHOMA; HIGH-RISK LYMPHOMA; REDUCED-INTENSITY; AUTOLOGOUS TRANSPLANTATION; CONDITIONING REGIMENS; EMISSION TOMOGRAPHY; RITUXIMAB ERA; RELAPSE; IMPACT; OUTCOMES;
D O I
10.1016/j.bulcan.2017.10.018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic hematopoietic cell transplantation is a potentially curative option, this is true particularly in the case of after autologous stem cell transplantation if remission can be achieved. Recently, novel agents such as anti-PD1 and BTK inhibitors have started to challenge the use of allogeneic hematopoietic cell transplantation for relapsed or refractory lymphoma. During the 2016 annual workshop of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC), we performed a comprehensive review of the literature published in the last 10 years and established guidelines to clarify the indications and transplant modalities in this setting. This section specifically reports on our conclusions regarding diffuse large B cell lymphoma.
引用
收藏
页码:S131 / S135
页数:5
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