Self-propelled particle model for cell-sorting phenomena

被引：98

作者：

Belmonte, Julio M. ^{[1
]}

Thomas, Gilberto L. ^{[1
]}

Brunnet, Leonardo G. ^{[1
]}

de Almeida, Rita M. C. ^{[1
]}

Chate, Hugues ^{[2
]}

机构：

[1] Univ Fed Rio Grande do Sul, Inst Fis, BR-91501970 Porto Alegre, RS, Brazil

[2] CEN Saclay, Serv Phys Etat Condense, F-91191 Gif Sur Yvette, France

来源：

PHYSICAL REVIEW LETTERS | 2008年 / 100卷 / 24期

关键词：

D O I：

10.1103/PhysRevLett.100.248702

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

A self-propelled particle model is introduced to study cell sorting occurring in some living organisms. This allows us to evaluate the influence of intrinsic cell motility separately from differential adhesion with fluctuations, a mechanism previously shown to be sufficient to explain a variety of cell rearrangement processes. We find that the tendency of cells to actively follow their neighbors greatly reduces segregation time scales. A finite-size analysis of the sorting process reveals clear algebraic growth laws as in physical phase-ordering processes, albeit with unusual scaling exponents.

引用

页数：4

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