The use of a lacertid lizard as a model for reptile ecotoxicology studies: Part 2-Biomarkers of exposure and toxicity among pesticide exposed lizards

被引：68

作者：

Amaral, Maria Jose ^{[1
,2
,3
]}

Bicho, Rita C. ^{[1
,2
]}

Carretero, Miguel A. ^{[3
]}

Sanchez-Hernandez, Juan C. ^{[4
]}

Faustino, Augusto M. R. ^{[5
]}

Soares, Amadeu M. V. M. ^{[1
,2
]}

Mann, Reinier M. ^{[1
,2
,6
,7
]}

机构：

[1] Univ Aveiro, CESAM, P-3810193 Aveiro, Portugal

[2] Univ Aveiro, Dept Biol, P-3810193 Aveiro, Portugal

[3] Univ Porto, CIBIO Ctr Invest Biodiversidade & Recursos Genet, P-4485661 Vairao, Portugal

[4] Univ Castilla La Mancha, Fac Ciencias Medio Ambiente & Bioquim, Lab Ecotoxicol, Toledo 45071, Spain

[5] Univ Porto, ICBAS, Dept Patol & Imunol Mol, P-4050123 Oporto, Portugal

[6] Univ Technol Sydney, Ctr Environm Sustainabil, Broadway, NSW 2007, Australia

[7] Hydrobiology, Auchenflower, Qld 4066, Australia

来源：

CHEMOSPHERE | 2012年 / 87卷 / 07期

关键词：

Pesticides; Field study; Reptiles; Multi-biomarker approach; Agro-environments; STANDARD METABOLIC-RATE; AFFECTS BODY CONDITION; OXIDATIVE STRESS; ENVIRONMENTAL PARASITOLOGY; LOCOMOTOR PERFORMANCE; HELMINTH COMMUNITIES; ANTIOXIDANT DEFENSE; PODARCIS-CARBONELLI; GLUTATHIONE; BIOMARKERS;

D O I：

10.1016/j.chemosphere.2012.01.048

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

As part of a wider study examining the impacts of corn pesticides on lacertid lizards in north-western Portugal, we examined various physiological, biochemical, and histological biomarkers of exposure and effect among field populations of Podarcis bocagei. Biomarkers included body condition index, standard metabolic rate, locomotor performance, parasitization, glutathione oxidative pathways and related enzyme activity, lipid peroxidation and liver and testis histology. Few of the various biomarkers investigated provided statistically significant evidence of toxic effect. However, using a weight of evidence approach, we conclude that pesticides are affecting lizards living in the vicinity of pesticide exposed corn agriculture sites. Lizards from these locations present a profile of animals under metabolic stress with reduced condition indices, increased standard metabolic rate, lower incidence of hepatocyte vacuolation, altered iron metabolism, increased activation of GSH oxidation pathways, and even increased prevalence of hemoparasites. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：765 / 774

页数：10

共 89 条

[11]

2-3, DOI 10.1002/(SICI)1520-6602(1998)1:53.0.CO

[12]

2-3]

[13] EVOLUTION OF SPRINT SPEED IN LACERTID LIZARDS - MORPHOLOGICAL, PHYSIOLOGICAL, AND BEHAVIORAL COVARIATION [J].

BAUWENS, D ;

GARLAND, T ;

CASTILLA, AM ;

VANDAMME, R .

EVOLUTION, 1995, 49 (05) :848-863

[14]

Bennett A.F., 1976, P127

[15]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[16] BIOCHEMICAL AND PHYSIOLOGICAL APPROACHES IN ECOTOXICOLOGY [J].

BROUWER, A ;

MURK, AJ ;

KOEMAN, JH .

FUNCTIONAL ECOLOGY, 1990, 4 (03) :275-281

[17]

Brown M., 1996, Assessing body condition in birds

[18] INDIVIDUAL AND POPULATION ENERGETICS OF A LIZARD ON A MEDITERRANEAN ISLET [J].

BROWN, RP ;

PEREZMELLADO, V ;

DIEGORASILLA, J ;

GARCIA, JA ;

NARANJO, A ;

SPEAKMAN, JR .

OECOLOGIA, 1992, 91 (04) :500-504

[19]

Congdon J.D., 1982, Biology of Reptilia, V13, P233

[20] A QUANTITATIVE ASSESSMENT OF HEMOSIDEROSIS IN WILD AND CAPTIVE BIRDS USING IMAGE-ANALYSIS [J].

CORK, SC ;

ALLEY, MR ;

STOCKDALE, PHG .

AVIAN PATHOLOGY, 1995, 24 (02) :239-254

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