CD4+ T cells limit the damage in influenza

被引:6
作者
Kelso, Anne [1 ]
机构
[1] World Hlth Org, Collaborating Ctr Reference & Res Influenza, Melbourne, Vic, Australia
关键词
A VIRUS; IMMUNITY; INFECTION; RESPONSES; H5N1;
D O I
10.1038/nm.2654
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Why do some influenza infections cause fatal disease and others barely a sniffle? Although viral virulence can vary, the immunological history of the host is also important. A new study in humans suggests that CD4(+) T lymphocytes activated during previous infections can limit disease severity in the absence of specific antibodies (pages 274-280).
引用
收藏
页码:200 / 202
页数:3
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