Could ochratoxin A in food commodities be the cause of chronic kidney disease in Sri Lanka?

被引：44

作者：

Wanigasuriya, Kamani P. ^{[1
]}

Peiris, Hemantha ^{[2
]}

Ileperuma, Nataka ^{[2
]}

Peiris-John, Roshini J. ^{[3
]}

Wickremasinghe, Rajitha ^{[4
]}

机构：

[1] Univ Sri Jayewardenepura, Dept Med, Fac Med Sci, Nugegoda, Sri Lanka

[2] Univ Sri Jayewardenepura, Dept Biochem, Fac Med Sci, Nugegoda, Sri Lanka

[3] Univ Sri Jayewardenepura, Dept Physiol, Fac Med Sci, Nugegoda, Sri Lanka

[4] Univ Sri Jayewardenepura, Dept Publ Hlth, Fac Med Sci, Nugegoda, Sri Lanka

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 102卷 / 07期

关键词：

Ochratoxin A; nephrotoxicity; cereals; pulses; food; Sri Lanka;

D O I：

10.1016/j.trstmh.2008.04.007

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Ochratoxin A (OA) is a naturally occurring mycotoxin with nephrotoxic properties that can contaminate plant food products. OA concentrations were assessed in commonly consumed food items in the North Central Province of Sri Lanka, where chronic kidney disease is diagnosed at epidemic proportions. Ninety-eight randomly selected food samples were analysed. Mycotoxin was detected in the extract by using a MycoMonitor Ochratoxin A ELISA assay kit (Helica Biosystems Inc., USA). The levels of OA found in these food commodities were below the recommended statutory maximum limit and are unlikely to be a potential risk factor for nephropathy in the North Central Province of Sri Lanka. (C) 2008 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：726 / 728

页数：3

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