Amino Acid Catalyzed Synthesis of 2,3-Dihydroquinazolin-4(1H)-one Derivatives

被引：8

作者：

Mustaque, K. Mohammed ^{[1
]}

Subramani, A. ^{[1
]}

Shabeer, T. K. ^{[1
]}

Thajudeen, H. ^{[1
]}

Ahamed, V. S. Jamal ^{[1
]}

机构：

[1] New Coll, PG & Res Dept Chem, Madras 600014, Tamil Nadu, India

来源：

LETTERS IN ORGANIC CHEMISTRY | 2018年 / 15卷 / 04期

关键词：

Amino acid; catalyst; 2,3-Dihydroquinazolin-4(1H)-ones; 2-aminobenzamide; ketones; water; EFFICIENT SYNTHESIS; IONIC LIQUIDS; FACILE; QUINAZOLINONES; MANNICH; ACCESS;

D O I：

10.2174/1570178614666171130154814

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, convenient and facile approach for the synthesis of a series of 2,3-dihydroquinazolin-4(1H)-ones in an environmentally benign method has been developed. This method involves a direct cyclocondensation of 2-aminobenzamide with aromatic aldehydes and ketones using aspartic acid as a catalyst in water.

引用

页码：246 / 250

页数：5

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