Future Directions in Mucormycosis Research

被引:38
作者
Kontoyiannis, Dimitrios P. [1 ]
Lewis, Russell E. [1 ]
Lotholary, Oliver [2 ]
Spellberg, Brad [3 ,4 ]
Petrikkos, Georgios [5 ]
Roillides, Emmanuel [6 ]
Ibrahim, Ashraf [3 ,4 ]
Walsh, Thomas J. [7 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Houston, TX 77030 USA
[2] Univ Paris, Hop Necker Enfants Malad, Serv Malad Infect & Trop, Paris, France
[3] Univ Calif Los Angeles, David Geffen Sch Med, Med Ctr,Div Gen Internal Med, Los Angeles Biomed Res Inst Harbor, Los Angeles, CA 90095 USA
[4] Harbor UCLA Med Ctr, Div Infect Dis, Torrance, CA USA
[5] Kapodistriakon Univ Athens, Thessaloniki, Greece
[6] Aristotle Univ Thessaloniki, Hippokrat Hosp, Dept Pediat 3, GR-54006 Thessaloniki, Greece
[7] Cornell Univ, Weill Med Coll, Div Infect Dis, New York Presbyterian Hosp, New York, NY 10021 USA
基金
美国国家卫生研究院;
关键词
CELL TRANSPLANT RECIPIENTS; INVASIVE FUNGAL-INFECTIONS; PULMONARY ZYGOMYCOSIS; ANTIFUNGAL THERAPY; RHIZOPUS-ORYZAE; AMPHOTERICIN-B; IN-VITRO; IDENTIFICATION; POSACONAZOLE; ASPERGILLUS;
D O I
10.1093/cid/cir886
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Mucormycosis has emerged as an important opportunistic infection, especially in severely immunosuppressed hosts. The evolving epidemiology, immunopathogenesis, molecular virulence studies, early diagnosis, and pitfalls in designing clinical studies of mucormycosis are discussed in this article.
引用
收藏
页码:S79 / S85
页数:7
相关论文
共 61 条
[31]   Increased culture recovery of zygomycetes under physiologic temperature conditions [J].
Kontoyiannis, Dimitrios P. ;
Chamilos, Georgios ;
Hassan, Saad A. ;
Lewis, Russell E. ;
Albert, Nathaniel D. ;
Tarrand, Jeffrey J. .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007, 127 (02) :208-212
[32]   Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001-2006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database [J].
Kontoyiannis, Dimitrios P. ;
Marr, Kieren A. ;
Park, Benjamin J. ;
Alexander, Barbara D. ;
Anaissie, Elias J. ;
Walsh, Thomas J. ;
Ito, James ;
Andes, David R. ;
Baddley, John W. ;
Brown, Janice M. ;
Brumble, Lisa M. ;
Freifeld, Alison G. ;
Hadley, Susan ;
Herwaldt, Loreen A. ;
Kauffman, Carol A. ;
Knapp, Katherine ;
Lyon, G. Marshall ;
Morrison, Vicki A. ;
Papanicolaou, Genovefa ;
Patterson, Thomas F. ;
Perl, Trish M. ;
Schuster, Mindy G. ;
Walker, Randall ;
Wannemuehler, Kathleen A. ;
Wingard, John R. ;
Chiller, Tom M. ;
Pappas, Peter G. .
CLINICAL INFECTIOUS DISEASES, 2010, 50 (08) :1091-1100
[33]   Zygomycosis in a Tertiary-Care Cancer Center in the era of Aspergillus-active antifungal therapy:: A case-control observational study of 27 recent cases [J].
Kontoyiannis, DP ;
Lionakis, MS ;
Lewis, RE ;
Chamilos, G ;
Healy, M ;
Perego, C ;
Safdar, A ;
Kantarjian, H ;
Champlin, R ;
Walsh, TJ ;
Raad, II .
JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (08) :1350-1360
[34]   Zygomycosis in the 1990s in a tertiary-care cancer center [J].
Kontoyiannis, DP ;
Wessel, VC ;
Bodey, GP ;
Rolston, KVI .
CLINICAL INFECTIOUS DISEASES, 2000, 30 (06) :851-856
[35]   Iron overload in hematologic malignancies and outcome of allogeneic hematopoietic stem cell transplantation [J].
Koreth, John ;
Antin, Joseph H. .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (03) :364-366
[36]   Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease [J].
Krishna, Gopal ;
Martinho, Monika ;
Chandrasekar, Pranatharthi ;
Ullmann, Andrew J. ;
Patino, Hernando .
PHARMACOTHERAPY, 2007, 27 (12) :1627-1636
[37]   Caspofungin-mediated β-glucan unmasking and enhancement of human polymorphonuclear neutrophil activity against Aspergillus and non-Aspergillus hyphae [J].
Lamaris, Gregory A. ;
Lewis, Russell E. ;
Chamilos, Georgios ;
May, Gregory S. ;
Safdar, Amar ;
Walsh, Thomas J. ;
Raad, Issam I. ;
Kontoyiannis, Dimitrios P. .
JOURNAL OF INFECTIOUS DISEASES, 2008, 198 (02) :186-192
[38]   Fatal Rhizopus Pneumonia in Allogeneic Stem Cell Transplant Patients Despite Posaconazole Prophylaxis: Two Cases and Review of the Literature [J].
Lekakis, Lazaros J. ;
Lawson, Amber ;
Prante, Jeanette ;
Ribes, Julie ;
Davis, Gregory J. ;
Monohan, Gregory ;
Baraboutis, Ioannis G. ;
Skoutelis, Athanasios T. ;
Howard, Dianna S. .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (08) :991-995
[39]   The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice [J].
Liu, Mingfu ;
Spellberg, Brad ;
Phan, Quynh T. ;
Fu, Yue ;
Fu, Yong ;
Lee, Amy S. ;
Edwards, John E., Jr. ;
Filler, Scott G. ;
Ibrahim, Ashraf S. .
JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (06) :1914-1924
[40]   Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication [J].
Ma, Li-Jun ;
Ibrahim, Ashraf S. ;
Skory, Christopher ;
Grabherr, Manfred G. ;
Burger, Gertraud ;
Butler, Margi ;
Elias, Marek ;
Idnurm, Alexander ;
Lang, B. Franz ;
Sone, Teruo ;
Abe, Ayumi ;
Calvo, Sarah E. ;
Corrochano, Luis M. ;
Engels, Reinhard ;
Fu, Jianmin ;
Hansberg, Wilhelm ;
Kim, Jung-Mi ;
Kodira, Chinnappa D. ;
Koehrsen, Michael J. ;
Liu, Bo ;
Miranda-Saavedra, Diego ;
O'Leary, Sinead ;
Ortiz-Castellanos, Lucila ;
Poulter, Russell ;
Rodriguez-Romero, Julio ;
Ruiz-Herrera, Jose ;
Shen, Yao-Qing ;
Zeng, Qiandong ;
Galagan, James ;
Birren, Bruce W. ;
Cuomo, Christina A. ;
Wickes, Brian L. .
PLOS GENETICS, 2009, 5 (07)