Impact of Cyclooxygenase-2 in Breast Cancer

被引：0

作者：

Hoellen, Friederike ^{[1
]}

Kelling, Katharina ^{[1
]}

Dittmer, Christine ^{[1
]}

Diedrich, Klaus ^{[1
]}

Friedrich, Michael ^{[2
]}

Thill, Marc ^{[1
]}

机构：

[1] Univ Hosp Schleswig Holstein, Dept Gynecol & Obstet, D-23538 Lubeck, Germany

[2] HELIOS Klinikum Krefeld, Krefeld, Germany

来源：

ANTICANCER RESEARCH | 2011年 / 31卷 / 12期

关键词：

Cyclooxygenase; COX-2; breast cancer; tumor; prostaglandin; carcinogenesis; CARCINOMA IN-SITU; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MESSENGER-RNA EXPRESSION; PROSTAGLANDIN METABOLIZING ENZYMES; COX-2 INHIBITOR CELECOXIB; VITAMIN-D-RECEPTOR; CELL-LINES; CYCLO-OXYGENASE-2; COX-2; AROMATASE EXPRESSION; OVARIAN-CARCINOMA;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prostaglandin metabolism plays a pivotal role in inflammatory processes and has also been demonstrated to have a role in carcinogenesis, tumor differentiation and tumor growth in breast cancer. Cyclooxygenase-2 (COX-2) is the key involved enzyme, as it triggers prostaglandin synthesis. We reviewed the current literature regarding the impact of prostaglandin metabolism on breast cancer and illustrated the current evidence of the COX-2 influence on breast cancer, delineating possible future prophylactic and therapeutic strategies.

引用

页码：4359 / 4367

页数：9

共 50 条

[41] Imaging and inhibiting cyclooxygenase-2 using aspirin-based fluorescent reporter for the treatment of breast cancer
Xia, Wenxi
Zhang, Shuangzhe
Fan, Jiangli
Li, Yueqing
Peng, Xiaojun
SENSORS AND ACTUATORS B-CHEMICAL, 2021, 329 (329)
[42] Cyclooxygenase-2 immunohistochemical expression is associated with worse prognosis in breast cancer Retrospective study and literature review
Al-Maghrabi, Jaudah
Khabaz, Mohamad N.
SAUDI MEDICAL JOURNAL, 2022, 43 (07) : 687 - 693
[43] Cyclooxygenase-2 Expression is not a Marker of Poor Survival in Lung Cancer
Turk, H. Mehmet
Camci, Celalettin
Sevinc, Alper
Bukyukberber, Suleyman
Sari, Ibrahim
Adli, Mustafa
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2012, 13 (01) : 315 - 318
[44] Selective inhibitors of cyclooxygenase-2
Talley, JJ
EXPERT OPINION ON THERAPEUTIC PATENTS, 1997, 7 (01) : 55 - 62
[45] Interplay between cyclooxygenase-2 and microRNAs in cancer
Gong, Zexiong
Huang, Weiguo
Wang, Baiyun
Liang, Na
Long, Songkai
Li, Wanjun
Zhou, Qier
MOLECULAR MEDICINE REPORTS, 2021, 23 (05)
[46] Cyclooxygenase-2 and gastrointestinal cancer
Mann, JR
DuBois, RN
CANCER JOURNAL, 2004, 10 (03) : 145 - 152
[47] Cyclooxygenase-2 Polymorphisms and Pancreatic Cancer Susceptibility
Ozhan, Gul
Lochan, Rajiv
Leathart, Julian B. S.
Charnley, Richard
Daly, Ann K.
PANCREAS, 2011, 40 (08) : 1289 - 1294
[48] Cyclooxygenase-2: a novel target for cancer chemotherapy?
Dempke, W
Rie, C
Grothey, A
Schmoll, HJ
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2001, 127 (07) : 411 - 417
[49] Blueberries inhibit cyclooxygenase-1 and cyclooxygenase-2 activity in human epithelial ovarian cancer
Lin, Wumei
Li, Zhigang
ONCOLOGY LETTERS, 2017, 13 (06) : 4897 - 4904
[50] Role of combination therapy with aromatase and cyclooxygenase-2 inhibitors in patients with metastatic breast cancer
Falandry, C.
Canney, P. A.
Freyer, G.
Dirix, L. Y.
ANNALS OF ONCOLOGY, 2009, 20 (04) : 615 - 620

← 1 2 3 4 5 →