Impact of Cyclooxygenase-2 in Breast Cancer

被引：0

作者：

Hoellen, Friederike ^{[1
]}

Kelling, Katharina ^{[1
]}

Dittmer, Christine ^{[1
]}

Diedrich, Klaus ^{[1
]}

Friedrich, Michael ^{[2
]}

Thill, Marc ^{[1
]}

机构：

[1] Univ Hosp Schleswig Holstein, Dept Gynecol & Obstet, D-23538 Lubeck, Germany

[2] HELIOS Klinikum Krefeld, Krefeld, Germany

来源：

ANTICANCER RESEARCH | 2011年 / 31卷 / 12期

关键词：

Cyclooxygenase; COX-2; breast cancer; tumor; prostaglandin; carcinogenesis; CARCINOMA IN-SITU; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MESSENGER-RNA EXPRESSION; PROSTAGLANDIN METABOLIZING ENZYMES; COX-2 INHIBITOR CELECOXIB; VITAMIN-D-RECEPTOR; CELL-LINES; CYCLO-OXYGENASE-2; COX-2; AROMATASE EXPRESSION; OVARIAN-CARCINOMA;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prostaglandin metabolism plays a pivotal role in inflammatory processes and has also been demonstrated to have a role in carcinogenesis, tumor differentiation and tumor growth in breast cancer. Cyclooxygenase-2 (COX-2) is the key involved enzyme, as it triggers prostaglandin synthesis. We reviewed the current literature regarding the impact of prostaglandin metabolism on breast cancer and illustrated the current evidence of the COX-2 influence on breast cancer, delineating possible future prophylactic and therapeutic strategies.

引用

页码：4359 / 4367

页数：9

共 50 条

[1] Role of cyclooxygenase-2 in breast cancer
Singh, B
Lucci, A
JOURNAL OF SURGICAL RESEARCH, 2002, 108 (01) : 173 - 179
[2] Cyclooxygenase-2 and the inflammogenesis of breast cancer
Harris, Randall E.
Casto, Bruce C.
Harris, Zachary M.
WORLD JOURNAL OF CLINICAL ONCOLOGY, 2014, 5 (04): : 677 - 692
[3] MicroRNA and cyclooxygenase-2 in breast cancer
Li, Wanjun
Zhang, Zhiwei
Wang, Baiyun
Liang, Na
Zhou, Qier
Long, Songkai
CLINICA CHIMICA ACTA, 2021, 522 : 36 - 44
[4] Cyclooxygenase-2 gene expression in human breast cancer
Parrett, ML
Harris, RE
Joarder, FS
Ross, MS
Clausen, KP
Robertson, FM
INTERNATIONAL JOURNAL OF ONCOLOGY, 1997, 10 (03) : 503 - 507
[5] Cyclooxygenase-2 as a therapeutic target against human breast cancer: A comprehensive review
Sahu, Ankita
Raza, Khalid
Pradhan, Dibyabhaba
Jain, Arun Kumar
Verma, Saurabh
WIRES MECHANISMS OF DISEASE, 2023, 15 (03):
[6] Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
Dai, Zhi-Jun
Ma, Xiao-Bin
Kang, Hua-Feng
Gao, Jie
Min, Wei-Li
Guan, Hai-Tao
Diao, Yan
Lu, Wang-Feng
Wang, Xi-Jing
CANCER CELL INTERNATIONAL, 2012, 12
[7] Cyclooxygenase-2 and chemoprevention of breast cancer
Davies, GLS
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2003, 86 (3-5) : 495 - 499
[8] Cyclooxygenase-2 Polymorphisms and Breast Cancer Associated Risk in Pakistani Patients
Moatter, Tariq
Aban, Muniba
Iqbal, Waseem
Pervez, Shahid
PATHOLOGY & ONCOLOGY RESEARCH, 2015, 21 (01) : 97 - 101
[9] Breast cancer - new aspects of tumor biology: are calcitriol and cyclooxygenase-2 possible targets for breast cancer?
Thill, M.
Terjung, A.
Friedrich, M.
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2014, 35 (04) : 341 - 358
[10] The Role of Cyclooxygenase-2 in Colorectal Cancer
Sheng, Juan
Sung, Hong
Yu, Fu-Bing
Li, Bo
Zhang, Yuan
Zhu, Ying-Ting
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2020, 17 (08): : 1095 - 1101

← 1 2 3 4 5 →