A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring

被引：22
作者：
Messina, M. A. [1 ]
Meli, C. [1 ]
Conoci, S. [2 ]
Petralia, S. [2 ]
机构：
[1] Azienda Osped Univ, Policlin Vittorio Emanuele, Via S Sofia 78, Catania, Italy
[2] STMicroelectronics, Str Primosole 50, I-95121 Catania, Italy
来源：
ANALYST | 2017年 / 142卷 / 24期
关键词：
TANDEM MASS-SPECTROMETRY; BLOOD PHENYLALANINE; HYDROXYLASE DEFICIENCY; PHENYLKETONURIA; BIOSENSOR; METAANALYSIS; SYSTEM;
D O I：
10.1039/c7an01115f
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A miniaturized paper-based lab-on-chip (LoC) was developed for the facile measurement of urinary Phe (phenylalanine) level on PKU (Phenylketonuria) treated patient. This system permits the monitoring of Phe in a dynamic range concentration of 20-3000 mu M.
引用
收藏
页码：4629 / 4632
页数：4
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