PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

被引：39

作者：

Verma, Sanny ^{[1
]}

Jain, Suman L. ^{[1
]}

Sain, Bir ^{[1
]}

机构：

[1] Indian Inst Petr, Div Chem Sci, Council Sci & Ind Res, Dehra Dun 248005, Uttar Pradesh, India

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 7卷

关键词：

heterocycles; metal free synthesis; multicomponent coupling; piperidine; recyclable catalyst; DIELS-ALDER REACTION; ONE-POT SYNTHESIS; CONCISE SYNTHESIS; ATOM; CYCLIZATION; ALKALOIDS; ACCESS;

D O I：

10.3762/bjoc.7.157

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

PEG-embedded potassium tribromide ([K(+)PEG]Br-3(-)) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and beta-keto ester. At the end of the reaction the [K(+)PEG]Br-3(-) was readily regenerated from the reaction mixture by treating the residue containing [K(+)PEG]Br- with molecular bromine.

引用

页码：1334 / 1341

页数：8

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