Endomicroscopy in the evaluation of Barrett's esophagus

被引：8

作者：

Dunbar, Kerry B. ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, VA N Texas Healthcare Syst, Dept Med, Div Gastroenterol & Hepatol, Dallas, TX 75216 USA

来源：

CURRENT OPINION IN GASTROENTEROLOGY | 2011年 / 27卷 / 04期

关键词：

Barrett's esophagus; confocal laser endomicroscopy; dysplasia; endomicroscopy; novel imaging; CONFOCAL LASER ENDOMICROSCOPY; HIGH-GRADE DYSPLASIA; IN-VIVO; COLORECTAL-CANCER; NEOPLASIA; ENDOSCOPY; CHROMOENDOSCOPY;

D O I：

10.1097/MOG.0b013e328347bac4

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Purpose of review Confocal laser endomicroscopy (CLE) can provide real-time, microscopic visualization of the gastrointestinal mucosa, allowing an endoscopic approach to the histologic evaluation of Barrett's esophagus and Barrett's esophagus-associated neoplasia. Recent findings Both endoscope-based (eCLE) and probe-based (pCLE) CLE systems have been used to evaluate Barrett's esophagus and Barrett's esophagus-associated neoplasia. Criteria for distinguishing Barrett's esophagus with neoplasia from nondysplastic Barrett's esophagus have been developed and validated for both eCLE and pCLE. Several studies have shown excellent detection of Barrett's esophagus neoplasia by CLE, and the technique may be used to guide endoscopic therapy. Advanced endomicroscopy systems and peptides and antibodies that target neoplasia are in development. Summary CLE has provided a new way of evaluating Barrett's esophagus and Barrett's esophagus-associated neoplasia and is being used to improve detection and management of neoplasia in Barrett's esophagus.

引用

页码：374 / 382

页数：9

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