Habitual Tea Consumption and Risk of Fracture in 0.5 Million Chinese Adults: A Prospective Cohort Study

被引:22
|
作者
Shen, Qian [1 ]
Yu, Canqing [1 ]
Guo, Yu [2 ]
Bian, Zheng [2 ]
Zhu, Nanbo [1 ]
Yang, Ling [3 ,4 ]
Chen, Yiping [3 ,4 ]
Luo, Guojin [5 ]
Li, Jianguo [5 ]
Qin, Yulu [6 ]
Chen, Junshi [7 ]
Chen, Zhengming [3 ,4 ]
Lv, Jun [1 ,8 ,9 ]
Li, Liming [1 ]
机构
[1] Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Hlth Sci Ctr, Beijing 100191, Peoples R China
[2] Chinese Acad Med Sci, Beijing 100191, Peoples R China
[3] Univ Oxford, Clin Trial Serv Unit, Nuffield Dept Populat Hlth, Oxford OX1 2JD, England
[4] Univ Oxford, Epidemiol Studies Unit CTSU, Nuffield Dept Populat Hlth, Oxford OX1 2JD, England
[5] Pengzhou Ctr Dis Control & Prevent, Pengzhou 611930, Sichuan, Peoples R China
[6] Liuzhou Ctr Dis Control & Prevent, NCDs Prevent & Control Dept, Liuzhou 545007, Guangxi, Peoples R China
[7] China Natl Ctr Food Safety Risk Assessment, Beijing 100191, Peoples R China
[8] Peking Univ, Key Lab Mol Cardiovasc Sci, Minist Educ, Beijing 100191, Peoples R China
[9] Peking Univ, Inst Environm Med, Beijing 100191, Peoples R China
基金
国家重点研发计划; 中国国家自然科学基金;
关键词
tea consumption; fracture; cohort study; HIP FRACTURE; POSTMENOPAUSAL WOMEN; CAFFEINE; OSTEOPOROSIS; COFFEE; OSTEOCLASTS; ACTIVATION; KADOORIE; ALCOHOL;
D O I
10.3390/nu10111633
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: Tea consumption may have favorable effects on risk of fracture. However, little is known about such association in Chinese adults. The aim of this study was to examine the association between tea consumption and risk of hospitalized fracture in Chinese adults. Methods: The present study included 453,625 participants from the China Kadoorie Biobank (CKB). Tea consumption was self-reported at baseline. Hospitalized fractures were ascertained through linkage with local health insurance claim databases. The results: During a median of 10.1 years of follow-up, we documented 12,130 cases of first-time any fracture hospitalizations, including 1376 cases of hip fracture. Compared with never tea consumers, daily tea consumption was associated with lower risk of any fracture (hazard ratio (HR): 0.88; 95% confidence interval (CI): 0.83, 0.93). Statistically significant reduced risk of hip fracture was shown among daily consumers who most commonly drank green tea (HR: 0.80; 95% CI: 0.65, 0.97) and those who had drunk tea for more than 30 years (HR: 0.68; 95% CI: 0.52, 0.87). Our conclusions: Habitual tea consumption was associated with moderately decreased risk of any fracture hospitalizations. Participants with decades of tea consumption and those who preferred green tea were also associated with lower risk of hip fracture.
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页数:11
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