Single-Atom Enzyme-Functionalized Solution-Gated Graphene Transistor for Real-Time Detection of Mercury Ion

被引：55

作者：

Yao, Lili ^{[1
]}

Gao, Shengjie ^{[1
]}

Liu, Shuai ^{[1
]}

Bi, Yulong ^{[1
]}

Wang, Rongrong ^{[1
]}

Qu, Hao ^{[1
]}

Wu, Yuen ^{[3
]}

Mao, Yu ^{[1
]}

Zheng, Lei ^{[1
,2
]}

机构：

[1] Hefei Univ Technol, Sch Food & Biol Engn, Hefei 230009, Peoples R China

[2] Anhui Modern Agr Ind Technol, Res Lab Agr Environm & Food Safety, Hefei 230009, Peoples R China

[3] Univ Sci & Technol China, iChEM Collaborat Innovat Ctr Chem Energy Mat, Dept Chem, Hefei 230009, Peoples R China

来源：

ACS APPLIED MATERIALS & INTERFACES | 2020年 / 12卷 / 05期

基金：

中国博士后科学基金;

关键词：

single-atom enzyme; graphene transistor; real-time detection; high sensitivity; high selectivity;

D O I：

10.1021/acsami.9b19434

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Mercury ion (Hg2+), a bioaccumulating and toxic heavy metal, can cause severe damages to the environment and human health. Therefore, development of high-performance Hg2+ sensors is highly desirable. Herein, we construct a uniform dodecahedral shaped N-doped carbon decorated by single Fe site enzyme (Fe-N-C SAE), which exhibits good performance for Hg2+ detection. The N atom on Fe-N-C SAE can specifically recognize Hg2+ through chelation between Hg2+ and N atom, while the catalytic site on the single-atom enzyme acts as a signal amplifier. The Fe-N-C SAE-functionalized solution-gated graphene transistor exhibits a dramatic improvement in the selectivity and sensitivity of the devices. The sensor can rapidly detect Hg2+ down to 1 nM within 2 s. Besides, a relatively good repeatability and reproducibility for the detection of Hg2+ have also been found in our sensor platform. Our findings expand the application of single-atom catalysts in the field of food safety and environmental monitoring.

引用

页码：6268 / 6275

页数：8