Electrophilic Cyclization of Buta-1,3-diynylarenes: Synthesis of Precursors of (Z)-3-Ene-1,5-diyne Systems Fused to Heterocycles

被引：25

作者：

Danilkina, Natalia A. ^{[2
]}

Braese, Stefan ^{[1
]}

Balova, Irina A. ^{[2
]}

机构：

[1] Karlsruhe Inst Technol, Inst Organ Chem, D-76131 Karlsruhe, Germany

[2] St Petersburg State Univ, Dept Organ Chem, St Petersburg 198504, Russia

来源：

SYNLETT | 2011年 / 04期

关键词：

electrophilic cyclization; alkynes; heterocycles; enediynes; TERMINAL ALKYNES; IODOCYCLIZATION; 3-IODOINDOLES;

D O I：

10.1055/s-0030-1259547

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, convenient, and promising strategy for the synthesis of 2-ethynyl-3-iodo-benzothiophenes, -benzofurans, and -indoles based on electrophilic cyclization of easily available ortho-functionalized (buta-1,3-diynyl) arenes was developed. The unique potential of using these compounds as starting materials for the synthesis of enediyne systems, containing thiophene, furan, and pyrrole units is demonstrated.

引用

页码：517 / 520

页数：4

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