Totaled Health Risks in Vascular Events Score Predicts Clinical Outcome and Symptomatic Intracranial Hemorrhage in Chinese Patients After Thrombolysis

被引：12

作者：

Chen, Weiqi

Pan, Yuesong

Zhao, Xingquan

Liao, Xiaoling

Liu, Liping

Wang, Chunjuan

Wang, Yilong

Wang, Yongjun ^{[1
]}

机构：

[1] Capital Med Univ, Dept Neurol, Beijing Tiantan Hosp, Beijing 100050, Peoples R China

来源：

STROKE | 2015年 / 46卷 / 03期

关键词：

prognosis; stroke; thrombolytic therapy; ISCHEMIC-STROKE PATIENTS; PLASMINOGEN-ACTIVATOR;

D O I：

10.1161/STROKEAHA.114.007979

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose-The performance of the Totaled Health Risks in Vascular Events (THRIVE) score in predicting clinical outcomes in Chinese patients with acute ischemic stroke post intravenous thrombolysis is unknown. Methods-Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study was used to compare the THRIVE score with other scores used to predict clinical outcomes and symptomatic intracranial hemorrhage after intravenous thrombolysis. Results-Among the 1128 patients with acute ischemic stroke who were included in this study, areas under the curve of the THRIVE score for symptomatic intracranial hemorrhage, 3-month poor functional outcomes, and death rate were 0.69, 0.71, and 0.78, respectively. The increased THRIVE score was related to the higher risk of developing symptomatic intracranial hemorrhage, poor functional outcomes, or death in patients with acute ischemic stroke at 3 months after thrombolysis. Conclusions-The THRIVE score predicted reliably the risks of developing symptomatic intracranial hemorrhage, poor functional outcome, or death after intravenous thrombolysis therapy in Chinese patients with acute ischemic stroke.

引用

页码：864 / 866

页数：3

共 11 条

[1] Predicting Long-Term Outcome after Endovascular Stroke Treatment: The Totaled Health Risks in Vascular Events Score [J].

Flint, A. C. ;

Cullen, S. P. ;

Faigeles, B. S. ;

Rao, V. A. .

AMERICAN JOURNAL OF NEURORADIOLOGY, 2010, 31 (07) :1192-1196

[2] THRIVE Score Predicts Ischemic Stroke Outcomes and Thrombolytic Hemorrhage Risk in VISTA [J].

Flint, Alexander C. ;

Faigeles, Bonnie S. ;

Cullen, Sean P. ;

Kamel, Hooman ;

Rao, Vivek A. ;

Gupta, Rishi ;

Smith, Wade S. ;

Bath, Philip M. ;

Donnan, Geoffrey A. .

STROKE, 2013, 44 (12) :3365-3369

[3] Predicting long-term outcome after acute ischemic stroke - A simple index works in patients from controlled clinical trials [J].

Koenig, Inke R. ;

Ziegler, Andreas ;

Bluhmki, Erich ;

Hacke, Werner ;

Bath, Philip M. W. ;

Sacco, Ralph L. ;

Diener, Hans C. ;

Weimar, Christian .

STROKE, 2008, 39 (06) :1821-1826

[4] Implementation and Outcome of Thrombolysis with Alteplase 3 to 4.5 h After Acute Stroke in Chinese Patients [J].

Liao, Xiao-Ling ;

Wang, Chun-Xue ;

Wang, Yi-Long ;

Wang, Chun-Juan ;

Zhao, Xing-Quan ;

Zhang, Li-Qun ;

Liu, Li-Ping ;

Pan, Yue-Song ;

Wang, Yong-Jun .

CNS NEUROSCIENCE & THERAPEUTICS, 2013, 19 (01) :43-47

[5] TISSUE-PLASMINOGEN ACTIVATOR FOR ACUTE ISCHEMIC STROKE [J].

MARLER, JR ;

BROTT, T ;

BRODERICK, J ;

KOTHARI, R ;

ODONOGHUE, M ;

BARSAN, W ;

TOMSICK, T ;

SPILKER, J ;

MILLER, R ;

SAUERBECK, L ;

JARRELL, J ;

KELLY, J ;

PERKINS, T ;

MCDONALD, T ;

RORICK, M ;

HICKEY, C ;

ARMITAGE, J ;

PERRY, C ;

THALINGER, K ;

RHUDE, R ;

SCHILL, J ;

BECKER, PS ;

HEATH, RS ;

ADAMS, D ;

REED, R ;

KLEI, M ;

HUGHES, S ;

ANTHONY, J ;

BAUDENDISTEL, D ;

ZADICOFF, C ;

RYMER, M ;

BETTINGER, I ;

LAUBINGER, P ;

SCHMERLER, M ;

MEIROSE, G ;

LYDEN, P ;

RAPP, K ;

BABCOCK, T ;

DAUM, P ;

PERSONA, D ;

BRODY, M ;

JACKSON, C ;

LEWIS, S ;

LISS, J ;

MAHDAVI, Z ;

ROTHROCK, J ;

TOM, T ;

ZWEIFLER, R ;

DUNFORD, J ;

ZIVIN, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (24) :1581-1587

[6] Stroke Prognostication using Age and NIH Stroke Scale SPAN-100 [J].

Saposnik, Gustavo ;

Guzik, Amy K. ;

Reeves, Mathew ;

Ovbiagele, Bruce ;

Johnston, S. Claiborne .

NEUROLOGY, 2013, 80 (01) :21-28

[7] Optimizing Prediction Scores for Poor Outcome After Intra-Arterial Therapy in Anterior Circulation Acute Ischemic Stroke [J].

Sarraj, Amrou ;

Albright, Karen ;

Barreto, Andrew D. ;

Boehme, Amelia K. ;

Sitton, Clark W. ;

Choi, Jeanie ;

Lutzker, Steven L. ;

Sun, Chung-Huan J. ;

Bibars, Wafi ;

Nguyen, Claude B. ;

Mir, Osman ;

Vahidy, Farhaan ;

Wu, Tzu-Ching ;

Lopez, George A. ;

Gonzales, Nicole R. ;

Edgell, Randall ;

Martin-Schild, Sheryl ;

Hallevi, Hen ;

Chen, Peng Roc ;

Dannenbaum, Mark ;

Saver, Jeffrey L. ;

Liebeskind, David S. ;

Nogueira, Raul G. ;

Gupta, Rishi ;

Grotta, James C. ;

Savitz, Sean I. .

STROKE, 2013, 44 (12) :3324-3330

[8] Predicting outcome of IV thrombolysis-treated ischemic stroke patients The DRAGON score [J].

Strbian, D. ;

Meretoja, A. ;

Ahlhelm, F. J. ;

Pitkaniemi, J. ;

Lyrer, P. ;

Kaste, M. ;

Engelter, S. ;

Tatlisumak, T. .

NEUROLOGY, 2012, 78 (06) :427-432

[9] Symptomatic intracranial hemorrhage after stroke thrombolysis: The SEDAN Score [J].

Strbian, Daniel ;

Engelter, Stefan ;

Michel, Patrik ;

Meretoja, Atte ;

Sekoranja, Lucka ;

Ahlhelm, Frank J. ;

Mustanoja, Satu ;

Kuzmanovic, Igor ;

Sairanen, Tiina ;

Forss, Nina ;

Cordier, Maria ;

Lyrer, Philippe ;

Kaste, Markku ;

Tatlisumak, Turgut .

ANNALS OF NEUROLOGY, 2012, 71 (05) :634-641

[10] Targeting Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Based on Risk of Intracranial Hemorrhage or Poor Functional Outcome An Analysis of the Third International Stroke Trial [J].

Whiteley, William N. ;

Thompson, Douglas ;

Murray, Gordon ;

Cohen, Geoff ;

Lindley, Richard I. ;

Wardlaw, Joanna ;

Sandercock, Peter .

STROKE, 2014, 45 (04) :1000-1006

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