Parathyroid transplantation in thyroid surgery

被引：36

作者：

Barczynski, Marcin ^{[1
]}

Golkowski, Filip ^{[2
]}

Nawrot, Ireneusz ^{[3
]}

机构：

[1] Jagiellonian Univ, Med Coll, Chair Gen Surg 3, Dept Endocrine Surg, Krakow, Poland

[2] Andrzej Frycz Modrzewski Krakow Univ, Fac Med, Dept Endocrinol & Internal Med, Krakow, Poland

[3] Med Univ Warsaw, Dept Gen Vasc & Transplantat Surg, Warsaw, Poland

来源：

GLAND SURGERY | 2017年 / 6卷 / 05期

关键词：

Thyroid surgery; hypoparathyroidism; parathyroid transplantation; intraoperative iPTH assay; POSTOPERATIVE HYPOCALCEMIA; HORMONE ASSAY; AUTOTRANSPLANTATION; TISSUE; ALLOTRANSPLANTATION; IMMUNOSUPPRESSION; HYPOPARATHYROIDISM; APPLICABILITY; AUTOGRAFTS; DISEASE;

D O I：

10.21037/gs.2017.06.07

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Permanent hypoparathyroidism following thyroid surgery is rare. Its prevalence is reported to be below 1-2% if surgery is performed by experienced thyroid surgeons. Parathyroid identification and preservation in situ with good vascular supply is the mainstay of safe thyroid surgery. However, if the parathyroid glands are damaged, autotransplantation should be undertaken to preserve their function. Parathyroid transplantation can be considered in three distinct modes of application: ( I) fresh parathyroid tissue autotransplantation during thyroidectomy in order to reduce the risk of permanent hypoparathyroidism; (II) cryopreserved parathyroid tissue autotransplantation in patients with permanent hypoparathyroidism; (III) parathyroid allotransplantation in patients with permanent hypoparathyroidism when cryopreserved parathyroid tissue is not available for grafting. Nowadays, allotransplantation of cultured parathyroid cells without immunosuppression should be taken into consideration in selected patients as an alternative to calcium and vitamin D3 supplementation in management of permanent hypoparathyroidism. This paper is aimed to provide a review of current status of various parathyroid transplantation techniques in thyroid surgery.

引用

页码：530 / 536

页数：7

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