Rho GTPase and Wnt signaling pathways in hepatocarcinogenesis

被引：5

作者：

Lechel, Andre ^{[1
,2
]}

Rudolph, Karl Lenhard ^{[1
,2
]}

机构：

[1] Inst Mol Med, D-89081 Ulm, Germany

[2] Max Planck Res Grp Stem Cell Aging, D-89081 Ulm, Germany

来源：

GASTROENTEROLOGY | 2008年 / 134卷 / 03期

关键词：

D O I：

10.1053/j.gastro.2008.01.055

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：875 / 878

页数：4

共 37 条

[1] Wnt signalling and the actin cytoskeleton [J].

Akiyama, T. ;

Kawasaki, Y. .

ONCOGENE, 2006, 25 (57) :7538-7544

[2] GSK-3β phosphorylation and alteration of β-catenin in hepatocellular carcinoma [J].

Ban, KC ;

Singh, H ;

Krishnan, R ;

Seow, HF .

CANCER LETTERS, 2003, 199 (02) :201-208

[3] Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β [J].

Behrens, J ;

Jerchow, BA ;

Würtele, M ;

Grimm, J ;

Asbrand, C ;

Wirtz, R ;

Kühl, M ;

Wedlich, D ;

Birchmeier, W .

SCIENCE, 1998, 280 (5363) :596-599

[4] IQGAP proteins are integral components of cytoskeletal regulation [J].

Briggs, MW ;

Sacks, DB .

EMBO REPORTS, 2003, 4 (06) :571-574

[5] New targets of β-catenin signaling in the liver are involved in the glutamine metabolism [J].

Cadoret, A ;

Ovejero, C ;

Terris, B ;

Souil, E ;

Lévy, L ;

Lamers, WH ;

Kitajewski, J ;

Kahn, A ;

Perret, C .

ONCOGENE, 2002, 21 (54) :8293-8301

[6]

Cadoret A, 2001, CANCER RES, V61, P3245

[7] Prickle-1 negatively regulates Wnt/β-catenin pathway by promoting dishevelled ubiquitination/degraclation in liver cancer [J].

Chan, David W. ;

Chan, Chung-Yiu ;

Yam, Judy W. P. ;

Ching, Yick-Pang ;

Ng, Irene O. L. .

GASTROENTEROLOGY, 2006, 131 (04) :1218-1227

[8] P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation [J].

Ching, Yick-Pang ;

Leong, Veronica Y. L. ;

Lee, Man-Fong ;

Xu, Hai-Tao ;

Jin, Dong-Yan ;

Ng, Irene Oi-Lin .

CANCER RESEARCH, 2007, 67 (08) :3601-3608

[9] Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma [J].

Ching, YP ;

Wong, CM ;

Chan, SF ;

Leung, THY ;

Ng, DCH ;

Jin, DY ;

Ng, IOL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (12) :10824-10830

[10] MOLECULAR PATHOGENESIS OF HEPATOCELLULAR-CARCINOMA IN HEPATITIS-B VIRUS TRANSGENIC MICE [J].

CHISARI, FV ;

KLOPCHIN, K ;

MORIYAMA, T ;

PASQUINELLI, C ;

DUNSFORD, HA ;

SELL, S ;

PINKERT, CA ;

BRINSTER, RL ;

PALMITER, RD .

CELL, 1989, 59 (06) :1145-1156

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