Vancomycin-induced severe thrombocytopenia in a young infant

被引：5

作者：

Chen, Quan-yao ^{[1
]}

Wan, Jun ^{[1
]}

Yang, Jian-hui ^{[1
]}

Lin, Min ^{[1
]}

Chen, Yao ^{[1
]}

机构：

[1] Xiamen Matern & Child Care Hosp, Dept Pharm, Xiamen, Fujian, Peoples R China

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2018年 / 51卷 / 06期

关键词：

Vancomycin; Infants; Thrombocytopenia; IMMUNE THROMBOCYTOPENIA;

D O I：

10.1590/0037-8682-0150-2018

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis. After 13 days of treatment with vancomycin, her platelet count reduced to 8 x 10(9)/L. Vancomycin was discontinued, and intravenous methylprednisolone was administered. The platelet count returned to normal after 4 days. Patients, especially young children, receiving vancomycin for a long clinical course should undergo careful monitoring of laboratory indicators and blood tests.

引用

页码：873 / 875

页数：3