Uncatalysed reactions in water: Part 2. Preparation of 3-carboxycoumarins

被引：89
作者：
Maggi, R [1 ]
Bigi, F [1 ]
Carloni, S [1 ]
Mazzacani, A [1 ]
Sartori, G [1 ]
机构：
[1] Univ Parma, Dipartimento Chim Organ & Ind, I-43100 Parma, Italy
来源：
GREEN CHEMISTRY | 2001年 / 3卷 / 04期
关键词：
D O I：
10.1039/b101822c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple, efficient and environmentally friendly procedure has been developed for the reaction of Meldrum's acid with salicylaldehydes. 3-Carboxycoumarins 5 were synthesised in high yields (78-96%) and excellent selectivities (95-98%) by carrying out the reaction in water at reflux for 10 h, avoiding the addition of any catalyst.
引用
收藏
页码：173 / 174
页数：2
相关论文
共 38 条
[1]  
[Anonymous], KIRK OTHMER ENCY CHE
[2]  
[Anonymous], KIRK OTHMER ENCY CHE
[3]   Zeolite as base catalyst: Nitroaldolic condensation [J].
Ballini, R ;
Bigi, F ;
Gogni, E ;
Maggi, R ;
Sartori, G .
JOURNAL OF CATALYSIS, 2000, 191 (02) :348-353
[4]   Reaction of aromatic amines and ethyl acetoacetate promoted by zeolite HSZ-360. Phosgene-free synthesis of symmetric diphenylureas [J].
Bigi, F ;
Maggi, R ;
Sartori, G ;
Zambonin, E .
CHEMICAL COMMUNICATIONS, 1998, (04) :513-514
[5]   Montmorillonite KSF as an inorganic, water stable, and reusable catalyst for the knoevenagel synthesis of coumarin-3-carboxylic acids [J].
Bigi, F ;
Chesini, L ;
Maggi, R ;
Sartori, G .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (03) :1033-1035
[6]   A revision of the Biginelli reaction under solid acid catalysis. Solvent-free synthesis of dihydropyrimidines over montmorillonite KSF [J].
Bigi, F ;
Carloni, S ;
Frullanti, B ;
Maggi, R ;
Sartori, G .
TETRAHEDRON LETTERS, 1999, 40 (17) :3465-3468
[7]   Reaction of aliphatic amines with acetoacetanilide in the presence of zeolite catalyst.: Solvent-free synthesis of symmetric N,N′-dialkylureas [J].
Bigi, F ;
Frullanti, B ;
Maggi, R ;
Sartori, G ;
Zambonin, E .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (03) :1004-1006
[8]   Trialkylamine controlled phenol-formaldehyde reaction over clay catalysts: Selective and environmentally benign synthesis of salicylic aldehydes [J].
Bigi, F ;
Conforti, ML ;
Maggi, R ;
Sartori, G .
TETRAHEDRON, 2000, 56 (17) :2709-2712
[9]   Clean synthesis in water: uncatalysed preparation of ylidenemalononitriles [J].
Bigi, F ;
Conforti, ML ;
Maggi, R ;
Piccinno, A ;
Sartori, G .
GREEN CHEMISTRY, 2000, 2 (03) :101-103
[10]  
BIGI F, 2000, GREEN CHEM CHALLENGI, P37
1234