A QTL with major effect on milk yield and composition maps to bovine Chromosome 14

被引：116

作者：

Coppieters, W ^{[1
]}

Riquet, J ^{[1
]}

Arranz, JJ ^{[1
]}

Berzi, P ^{[1
]}

Cambisano, N ^{[1
]}

Grisart, B ^{[1
]}

Karim, L ^{[1
]}

Marcq, F ^{[1
]}

Moreau, L ^{[1
]}

Nezer, C ^{[1
]}

Simon, P ^{[1
]}

Vanmanshoven, P ^{[1
]}

Wagenaar, D ^{[1
]}

Georges, M ^{[1
]}

机构：

[1] Univ Liege B43, Fac Med Vet, Dept Genet, B-4000 Liege, Belgium

来源：

MAMMALIAN GENOME | 1998年 / 9卷 / 07期

关键词：

D O I：

10.1007/s003359900815

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A whole genome scan was undertaken in a granddaughter design comprising 1158 progeny-tested bulls in order to map QTL influencing milk yield and composition. In this paper we report the identification of a locus on the centromeric end of bovine Chromosome (Chr) 14, with major effect on fat and protein percentage as well as milk yield. The genuine nature of this QTL was verified using the grand(2)-daughter design, that is, by tracing the segregating QTL alleles from heterozygous grandsires to their maternal grandsons and confirming the predicted QTL allele substitution effect.

引用

页码：540 / 544

页数：5

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