Novel therapeutics for the treatment of paediatric pulmonary arterial hypertension

被引：1

作者：

Rosenzweig, EB ^{[1
]}

Barst, RJ ^{[1
]}

机构：

[1] Babies & Childrens Hosp New York, New York Presbyterian Hosp, Div Pediat Cardiol, New York, NY 10032 USA

来源：

EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2001年 / 10卷 / 05期

关键词：

endothelin receptor antagonists; paediatrics; prostacyclin; prostacyclin analogues; pulmonary arterial hypertension; pulmonary vasodilator treatment;

D O I：

10.1517/13543784.10.5.811

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The treatment of paediatric pulmonary arterial hypertension is challenging due to the serious nature of the disease, its rapid progression and the limited treatment options available. However. recent advances in the treatment of pulmonary arterial hypertension may offer significant improvements for patients suffering from this condition. Novel treatment options include prostacyclin analogues and endothelin receptor antagonists. A comprehensive review of the nem er agents, with an emphasis on the pathobiology/pathophysiology of pulmonary arterial hypertension provides insight into future management of paediatric pulmonary arterial hypertension.

引用

页码：811 / 823

页数：13

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